Protein: VGFR1
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)

Gene: VGFR1, FLT1
Organism: Homo sapiens
Interactions: 173
UniProt ID: P17948

Gene Ontology (top 5):
GO:0002040 - sprouting angiogenesis
GO:0002548 - monocyte chemotaxis
GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0005021 - vascular endothelial growth factor receptor activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

585434

VEGFA
Vascular endothelial growth factor A, long form

12

20

Small-scale

0.980

High

609964

PLGF
Placenta growth factor

4

20

Small-scale

0.882

High

609965

VEGFB
Vascular endothelial growth factor B

2

18

Small-scale

0.812

High

609953

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

20

Small-scale

0.775

High

609955

VGFR2
Vascular endothelial growth factor receptor 2

2

17

Small-scale

0.768

High

609984

SHC2
SHC-transforming protein 2

2

20

Small-scale

0.754

High

609985

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

9

Small-scale

0.730

High

609993

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

2

20

Small-scale

0.712

High

610040

SRPK1
SRSF protein kinase 1

1

18

High-throughput

0.710

High

609946

VGFR1
Vascular endothelial growth factor receptor 1

1

16

Small-scale

0.692

High

609948

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

18

Small-scale

0.680

High

609961

CRKL
Crk-like protein

1

20

Small-scale

0.665

High

609951

CBL
E3 ubiquitin-protein ligase CBL

3

20

Small-scale

0.646

High

609954

SHC1
SHC-transforming protein 1

1

20

Small-scale

0.621

High

164244

NRP1
Neuropilin-1

1

9

Small-scale

0.618

High

376474

LDLR
Low-density lipoprotein receptor

1

3

Small-scale

0.618

High

440349

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.618

High

443165

CDK1
Cyclin-dependent kinase 1

1

8

High-throughput

0.618

High

462979

YES
Tyrosine-protein kinase Yes

1

20

Small-scale

0.618

High

609950

RAB6A
Ras-related protein Rab-6A

1

7

High-throughput

0.618

High

609952

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

17

Small-scale

0.618

High

609957

STAT3
Signal transducer and activator of transcription 3

1

13

Small-scale

0.618

High

609959

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

13

Small-scale

0.618

High

609968

DYN2
Dynamin-2

1

10

High-throughput

0.618

High

609994

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

3

High-throughput

0.618

High

610044

OSBL8
Oxysterol-binding protein-related protein 8

1

4

High-throughput

0.618

High

610066

RAB21
Ras-related protein Rab-21

1

10

High-throughput

0.618

High

444895

S10A9
Protein S100-A9

1

2

Small-scale

0.575

High

610029

ROBO4
Roundabout homolog 4

1

9

Small-scale

0.575

High

318950

MICA2
[F-actin]-monooxygenase MICAL2

1

9

Small-scale

0.553

High

609962

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

11

High-throughput

0.536

High

518806

CCL3
C-C motif chemokine 3

1

3

High-throughput

0.536

High

609995

SG2A2
Mammaglobin-A

1

2

High-throughput

0.536

High

610064

FBX2
F-box only protein 2

1

7

High-throughput

0.536

High

610036

MF14A
Hippocampus abundant transcript 1 protein

1

5

High-throughput

0.514

High

610069

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.513

High

228439

LANC1
Glutathione S-transferase LANCL1

1

2

High-throughput

0.500

High

285582

BAF
Barrier-to-autointegration factor

1

3

High-throughput

0.500

High

610027

CA054
Uncharacterized protein C1orf54

1

1

High-throughput

0.489

High

220856

XPOT
Exportin-T

1

10

High-throughput

0.479

High

221523

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

4

High-throughput

0.479

High

227792

MYO1B
Unconventional myosin-Ib

1

6

High-throughput

0.479

High

238381

RAD21
Double-strand-break repair protein rad21 homolog

1

2

High-throughput

0.479

High

240694

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

243533

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

7

High-throughput

0.479

High

273483

DJC13
DnaJ homolog subfamily C member 13

1

8

High-throughput

0.479

High

610058

DDX56
Probable ATP-dependent RNA helicase DDX56

1

12

High-throughput

0.479

High

291206

NU155
Nuclear pore complex protein Nup155

1

6

High-throughput

0.479

High

333931

SMC2
Structural maintenance of chromosomes protein 2

1

11

High-throughput

0.479

High

403124

APOB
Apolipoprotein B-100

1

1

High-throughput

0.479

High

426197

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

4

High-throughput

0.479

High

480692

LEG1
Galectin-1

1

8

Small-scale

0.479

High

483512

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

5

High-throughput

0.479

High

538516

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

2

High-throughput

0.479

High

557843

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

566544

PDIA4
Protein disulfide-isomerase A4

1

11

High-throughput

0.479

High

608821

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

11

High-throughput

0.479

High

609947

ARF4
ADP-ribosylation factor 4

1

11

High-throughput

0.479

High

609949

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

5

High-throughput

0.479

High

609956

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

609958

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

7

High-throughput

0.479

High

609960

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

4

High-throughput

0.479

High

609966

EMD
Emerin

1

5

High-throughput

0.479

High

609967

SERPH
Serpin H1

1

6

High-throughput

0.479

High

609969

DHB4
Peroxisomal multifunctional enzyme type 2

1

5

High-throughput

0.479

High

609970

BLM
RecQ-like DNA helicase BLM

1

4

High-throughput

0.479

High

609971

SYRC
Arginine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

609972

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

6

High-throughput

0.479

High

609973

PSA
Puromycin-sensitive aminopeptidase

1

2

High-throughput

0.479

High

609974

RBM11
Splicing regulator RBM11

1

2

High-throughput

0.479

High

609976

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

6

High-throughput

0.479

High

609979

ARF6
ADP-ribosylation factor 6

1

11

High-throughput

0.479

High

609980

ERF1
Eukaryotic peptide chain release factor subunit 1

1

3

High-throughput

0.479

High

609981

RACK1
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.479

High

609982

PRKDC
DNA-dependent protein kinase catalytic subunit

1

9

High-throughput

0.479

High

609986

TFAM
Transcription factor A, mitochondrial

1

2

High-throughput

0.479

High

609987

PURA
Transcriptional activator protein Pur-alpha

1

2

High-throughput

0.479

High

609988

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

11

High-throughput

0.479

High

609992

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

1

2

High-throughput

0.479

High

609998

FHL3
Four and a half LIM domains protein 3

1

11

High-throughput

0.479

High

609999

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

3

High-throughput

0.479

High

610000

SMC1A
Structural maintenance of chromosomes protein 1A

1

11

High-throughput

0.479

High

610001

CND2
Condensin complex subunit 2

1

3

High-throughput

0.479

High

610002

SYK
Lysine--tRNA ligase

1

5

High-throughput

0.479

High

610003

PCH2
Pachytene checkpoint protein 2 homolog

1

4

High-throughput

0.479

High

610006

NU188
Nucleoporin NUP188

1

2

High-throughput

0.479

High

610008

RN213
E3 ubiquitin-protein ligase RNF213

1

1

High-throughput

0.479

High

610010

C1TM
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

1

3

High-throughput

0.479

High

610012

DHX30
ATP-dependent RNA helicase DHX30

1

7

High-throughput

0.479

High

610014

MON2
Protein MON2 homolog

1

4

High-throughput

0.479

High

610019

NUP93
Nuclear pore complex protein Nup93

1

5

High-throughput

0.479

High

610022

COQ8A
Atypical kinase COQ8A, mitochondrial

1

1

High-throughput

0.479

High

610024

DDX54
ATP-dependent RNA helicase DDX54

1

14

High-throughput

0.479

High

610028

DNJC9
DnaJ homolog subfamily C member 9

1

17

High-throughput

0.479

High

610031

GCN1
Stalled ribosome sensor GCN1

1

8

High-throughput

0.479

High

610032

NU205
Nuclear pore complex protein Nup205

1

7

High-throughput

0.479

High

610033

ARHG2
Rho guanine nucleotide exchange factor 2

1

17

High-throughput

0.479

High

610034

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

4

High-throughput

0.479

High

610035

DDX27
Probable ATP-dependent RNA helicase DDX27

1

14

High-throughput

0.479

High

610042

MMS19
MMS19 nucleotide excision repair protein homolog

1

3

High-throughput

0.479

High

610043

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

6

High-throughput

0.479

High

610045

DDX47
Probable ATP-dependent RNA helicase DDX47

1

9

High-throughput

0.479

High

610046

PDCL3
Phosducin-like protein 3

1

2

High-throughput

0.479

High

610047

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

7

High-throughput

0.479

High

610049

YTDC2
3'-5' RNA helicase YTHDC2

1

7

High-throughput

0.479

High

610050

XPO5
Exportin-5

1

10

High-throughput

0.479

High

610052

SAR1A
Small COPII coat GTPase SAR1A

1

18

High-throughput

0.479

High

610054

MDN1
Midasin

1

8

High-throughput

0.479

High

610055

DD19A
ATP-dependent RNA helicase DDX19A

1

4

High-throughput

0.479

High

610056

FANCI
Fanconi anemia group I protein

1

6

High-throughput

0.479

High

610061

ABCF2
ATP-binding cassette sub-family F member 2

1

2

High-throughput

0.479

High

610063

BAZ1B
Tyrosine-protein kinase BAZ1B

1

9

High-throughput

0.479

High

610067

DOP1B
Protein DOP1B

1

1

High-throughput

0.479

High

610068

NOC2L
Nucleolar complex protein 2 homolog

1

2

High-throughput

0.479

High

610070

HYOU1
Hypoxia up-regulated protein 1

1

15

High-throughput

0.479

High

610071

TNPO3
Transportin-3

1

14

High-throughput

0.479

High

610074

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

3

High-throughput

0.479

High

336343

SVIL
Supervillin

1

0

High-throughput

0.458

High

609963

PSB3
Proteasome subunit beta type-3

1

0

High-throughput

0.458

High

609977

MGN
Protein mago nashi homolog

1

0

High-throughput

0.458

High

609989

LGUL
Lactoylglutathione lyase

1

0

High-throughput

0.458

High

609990

GFPT1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1

1

0

High-throughput

0.458

High

610021

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

610059

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

0

High-throughput

0.458

High

610073

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.458

High

322801

MTCL2
Microtubule cross-linking factor 2

1

7

Small-scale

0.445

High

456598

ANXA2
Annexin A2

1

1

Small-scale

0.445

High

610023

CIP2A
Protein CIP2A

1

2

Small-scale

0.445

High

50488

HACL2
2-hydroxyacyl-CoA lyase 2

1

1

High-throughput

0.437

High

126056

AP3B1
AP-3 complex subunit beta-1

1

3

High-throughput

0.437

High

137645

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

5

High-throughput

0.437

High

158771

AP3D1
AP-3 complex subunit delta-1

1

8

High-throughput

0.437

High

244312

NPA1P
Nucleolar pre-ribosomal-associated protein 1

1

1

High-throughput

0.437

High

255567

DPM1
Dolichol-phosphate mannosyltransferase subunit 1

1

10

High-throughput

0.437

High

277550

H2AY
Core histone macro-H2A.1

1

3

High-throughput

0.437

High

290444

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.437

High

338047

NSA2
Ribosome biogenesis protein NSA2 homolog

1

2

High-throughput

0.437

High

468991

SRPRA
Signal recognition particle receptor subunit alpha

1

4

High-throughput

0.437

High

539514

PYGB
Glycogen phosphorylase, brain form

1

3

High-throughput

0.437

High

566912

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

3

High-throughput

0.437

High

609975

TMM33
Transmembrane protein 33

1

2

High-throughput

0.437

High

609978

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

4

High-throughput

0.437

High

609983

RT34
Small ribosomal subunit protein mS34

1

1

High-throughput

0.437

High

609991

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

1

5

High-throughput

0.437

High

609996

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.437

High

609997

PWP1
Periodic tryptophan protein 1 homolog

1

7

High-throughput

0.437

High

610004

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

13

High-throughput

0.437

High

610005

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

4

High-throughput

0.437

High

610011

TM10C
tRNA methyltransferase 10 homolog C

1

2

High-throughput

0.437

High

610013

TRM1L
tRNA

1

2

High-throughput

0.437

High

610017

PHF6
PHD finger protein 6

1

5

High-throughput

0.437

High

610020

KRI1
Protein KRI1 homolog

1

6

High-throughput

0.437

High

610025

IPO4
Importin-4

1

7

High-throughput

0.437

High

610030

RT27
Small ribosomal subunit protein mS27

1

2

High-throughput

0.437

High

610037

ZN512
Zinc finger protein 512

1

2

High-throughput

0.437

High

610039

RBM14
RNA-binding protein 14

1

7

High-throughput

0.437

High

610041

STRBP
Spermatid perinuclear RNA-binding protein

1

3

High-throughput

0.437

High

610051

SSF1
Suppressor of SWI4 1 homolog

1

1

High-throughput

0.437

High

610053

BAZ1A
Bromodomain adjacent to zinc finger domain protein 1A

1

12

High-throughput

0.437

High

610057

RBM28
RNA-binding protein 28

1

1

High-throughput

0.437

High

610060

DHCR7
7-dehydrocholesterol reductase

1

2

High-throughput

0.437

High

610062

SEC63
Translocation protein SEC63 homolog

1

12

High-throughput

0.437

High

610065

MRT4
mRNA turnover protein 4 homolog

1

4

High-throughput

0.437

High

610072

SRPRB
Signal recognition particle receptor subunit beta

1

19

High-throughput

0.437

High

610015

TMC4
Voltage-gated chloride channel TMC4

1

0

Small-scale

0.426

High

610026

SCRB1
Scavenger receptor class B member 1

1

0

Small-scale

0.426

High

610038

SPB12
Serpin B12

1

0

Small-scale

0.426

High

610016

ZN467
Zinc finger protein 467

1

0

High-throughput

0.279

Low

610009

CC137
Coiled-coil domain-containing protein 137

1

0

High-throughput

0.249

Low

610018

RM41
Large ribosomal subunit protein mL41

1

0

High-throughput

0.249

Low

610007

TMCO4
Transmembrane and coiled-coil domain-containing protein 4

1

0

Small-scale

0.232

Low

610048

TM245
Transmembrane protein 245

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025