HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: SRPK2 (P78362)
SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]
Gene: SRPK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 688
+	Hs
		652026 RFA1_HUMAN (1-616): 0: 781: 100.00		SRPK1_HUMAN (27-688): 1.57e-125: 388: 53.22
+	Hs
		625131 RFA1_HUMAN (1-616): 0: 781: 100.00		CDK2_HUMAN (378-687): 1.93e-91: 288: 17.14
+	Hs
		650723 RFA1_HUMAN (1-616): 0: 781: 100.00		KS6A3_HUMAN (2-362): 2.51e-78: 266: 13.83
+	Hs
		652560 RFA1_HUMAN (1-616): 0: 781: 100.00		KS6A6_HUMAN (2-362): 5.53e-77: 263: 15.92
+	Hs
		651283 RFA1_HUMAN (1-616): 0: 781: 100.00		KS6A1_HUMAN (2-359): 1.19e-76: 262: 14.13
+	Hs
		270375 RFA1_HUMAN (1-616): 0: 781: 100.00		KS6A5_HUMAN (3-343): 1.04e-72: 252: 14.52
+	Hs
		651838 RFA1_HUMAN (1-616): 0: 781: 100.00		DYRK2_HUMAN (51-234): 1.48e-62: 221: 29.35
+	Hs
		650672 RFA1_HUMAN (1-616): 0: 781: 100.00		CLK3_HUMAN (62-240): 6.66e-62: 220: 31.11
+	Hs
		651168 RFA1_HUMAN (1-616): 0: 781: 100.00		CDK13_HUMAN (373-687): 1.6e-54: 204: 15.85
+	Hs
		652443 RFA1_HUMAN (1-616): 0: 781: 100.00		CDK12_HUMAN (291-687): 5.8e-54: 203: 13.17
+	Hs
		651139 RFA1_HUMAN (1-616): 0: 781: 100.00		KCC2G_HUMAN (376-686): 1.18e-29: 126: 16.51
+	Zm
		2187 A0A1D6EZA2_MAIZE (83-505): 1.89e-78: 267: 14.57		A0A0B4J3D8_MAIZE (379-687): 1.13e-45: 170: 11.71