HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: PAK2 (Q13177)
Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]
Gene: PAK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 524
+	Hs
		650467 RFA1_HUMAN (1-616): 0: 781: 100.00		AKT2_HUMAN (141-523): 2.01e-138: 410: 22.79
+	Hs
		650466 RFA1_HUMAN (1-616): 0: 781: 100.00		AKT1_HUMAN (141-523): 1.99e-133: 397: 21.83
+	Hs
		568552 RFA1_HUMAN (1-616): 0: 781: 100.00		KAPCA_HUMAN (207-520): 9.62e-131: 385: 22.91
+	Hs
		652477 RFA1_HUMAN (1-616): 0: 781: 100.00		STK26_HUMAN (241-513): 3.68e-66: 221: 45.09
+	Hs
		652744 RFA1_HUMAN (1-616): 0: 781: 100.00		STK24_HUMAN (243-513): 1.32e-65: 221: 45.06
+	Hs
		330864 RFA1_HUMAN (1-616): 0: 781: 100.00		PAK4_HUMAN (67-236): 2.65e-10: 64.9: 21.55
+	Zm
		2187 A0A1D6EZA2_MAIZE (83-505): 1.89e-78: 267: 14.57		A0A0B4J3D8_MAIZE (239-510): 5.06e-133: 395: 28.42