Protein: LRC8E
Volume-regulated anion channel subunit LRRC8E (Leucine-rich repeat-containing protein 8E)

Gene: LRC8E, LRRC8E
Organism: Homo sapiens
Interactions: 94
UniProt ID: Q6NSJ5

Gene Ontology (top 5):
GO:0005225 - volume-sensitive anion channel activity
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1155890

LRC8B
Volume-regulated anion channel subunit LRRC8B

2

19

High-throughput

0.811

High

1155915

TRIM2
Tripartite motif-containing protein 2

4

4

High-throughput

0.697

High

353426

PIGR
Polymeric immunoglobulin receptor

1

1

High-throughput

0.691

High

488262

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

2

High-throughput

0.691

High

540303

GPIX
Platelet glycoprotein IX

1

7

High-throughput

0.691

High

1155892

LRC55
Leucine-rich repeat-containing protein 55

1

19

High-throughput

0.691

High

1155894

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.691

High

1155920

RXFP1
Relaxin receptor 1

1

20

High-throughput

0.691

High

1155924

CLC2D
C-type lectin domain family 2 member D

1

1

High-throughput

0.691

High

121175

LEG8
Galectin-8

3

5

High-throughput

0.667

High

1155896

LRC8A
Volume-regulated anion channel subunit LRRC8A

1

19

Small-scale

0.665

High

252748

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

3

3

High-throughput

0.656

High

1155898

LNX2
Ligand of Numb protein X 2

3

13

High-throughput

0.653

High

513873

DMD
Dystrophin

2

3

High-throughput

0.628

High

793188

PI2R
Prostacyclin receptor

2

7

High-throughput

0.628

High

802335

5HT3A
5-hydroxytryptamine receptor 3A

2

8

High-throughput

0.628

High

878529

PSA
Puromycin-sensitive aminopeptidase

2

4

High-throughput

0.628

High

1155916

NMUR2
Neuromedin-U receptor 2

2

2

High-throughput

0.628

High

262179

TRIM3
Tripartite motif-containing protein 3

2

4

High-throughput

0.606

High

946371

GPSM2
G-protein-signaling modulator 2

2

2

High-throughput

0.606

High

596062

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

2

0

High-throughput

0.602

High

901586

LYSC
Lysozyme C

1

0

High-throughput

0.578

High

354078

IGHA1
Immunoglobulin heavy constant alpha 1

1

1

High-throughput

0.575

High

354163

IGHA2
Immunoglobulin heavy constant alpha 2

1

1

High-throughput

0.575

High

232684

TBCD4
TBC1 domain family member 4

2

1

High-throughput

0.574

High

297238

DDHD2
Phospholipase DDHD2

2

1

High-throughput

0.574

High

1155891

DLK2
Protein delta homolog 2

2

4

High-throughput

0.574

High

172050

GP182
G-protein coupled receptor 182

1

5

High-throughput

0.536

High

234018

O10H2
Olfactory receptor 10H2

1

5

High-throughput

0.536

High

326093

TSN15
Tetraspanin-15

1

3

High-throughput

0.536

High

344868

CYTS
Cystatin-S

1

1

High-throughput

0.536

High

344990

CYTN
Cystatin-SN

1

1

High-throughput

0.536

High

504252

HSP7C
Heat shock cognate 71 kDa protein

1

8

High-throughput

0.536

High

530249

ICAM2
Intercellular adhesion molecule 2

1

2

High-throughput

0.536

High

558738

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

7

High-throughput

0.536

High

564094

HSP76
Heat shock 70 kDa protein 6

1

8

High-throughput

0.536

High

626533

FPR2
N-formyl peptide receptor 2

1

8

High-throughput

0.536

High

654433

CALX
Calnexin

1

3

High-throughput

0.536

High

676807

SSR1
Somatostatin receptor type 1

1

4

High-throughput

0.536

High

798497

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

2

High-throughput

0.536

High

871618

HSP72
Heat shock-related 70 kDa protein 2

1

8

High-throughput

0.536

High

944143

KCJ10
ATP-sensitive inward rectifier potassium channel 10

1

4

High-throughput

0.536

High

1117543

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

2

High-throughput

0.536

High

1155901

SIDT2
SID1 transmembrane family member 2

1

3

High-throughput

0.536

High

1155902

OR4N2
Olfactory receptor 4N2

1

2

High-throughput

0.536

High

1155905

LPAR1
Lysophosphatidic acid receptor 1

1

4

High-throughput

0.536

High

1155914

TM2D3
TM2 domain-containing protein 3

1

1

High-throughput

0.536

High

1155919

TTYH1
Protein tweety homolog 1

1

4

High-throughput

0.536

High

1155922

HCST
Hematopoietic cell signal transducer

1

3

High-throughput

0.536

High

1155929

O10H1
Olfactory receptor 10H1

1

6

High-throughput

0.536

High

1155903

OR4D6
Olfactory receptor 4D6

1

2

High-throughput

0.515

High

131911

UPK2
Uroplakin-2

1

0

High-throughput

0.513

High

364689

TRFL
Lactotransferrin

1

0

High-throughput

0.513

High

513744

CP19A
Aromatase

1

0

High-throughput

0.513

High

1053767

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.513

High

1092760

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.513

High

1125017

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1155893

TMC6
Transmembrane channel-like protein 6

1

0

High-throughput

0.513

High

1155907

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1155908

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.513

High

1155911

SGCZ
Zeta-sarcoglycan

1

0

High-throughput

0.513

High

1155912

P2RX4
P2X purinoceptor 4

1

0

High-throughput

0.513

High

1155918

S22A4
Solute carrier family 22 member 4

1

0

High-throughput

0.513

High

1155921

KCMB3
Calcium-activated potassium channel subunit beta-3

1

0

High-throughput

0.513

High

1155923

SHPK
Sedoheptulokinase

1

0

High-throughput

0.513

High

1155926

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.513

High

573312

TCPA
T-complex protein 1 subunit alpha

1

2

High-throughput

0.489

High

677830

LCN1
Lipocalin-1

1

1

High-throughput

0.489

High

737372

LONM
Lon protease homolog, mitochondrial

1

3

High-throughput

0.489

High

1155927

SGT1
Protein SGT1 homolog

1

17

High-throughput

0.489

High

1155928

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

73145

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

11

High-throughput

0.479

High

1155897

RHG24
Rho GTPase-activating protein 24

1

3

High-throughput

0.479

High

1155895

NUTM1
NUT family member 1

1

0

High-throughput

0.460

High

941043

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

483789

HS71B
Heat shock 70 kDa protein 1B

1

8

High-throughput

0.445

High

1080037

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.437

High

209249

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.426

High

92671

E9PNY5
Low affinity immunoglobulin gamma Fc region receptor III-A

1

3

High-throughput

0.407

High

1155906

ESR2
Estrogen receptor beta

1

9

High-throughput

0.407

High

1155925

TRM6
tRNA

2

0

High-throughput

0.328

High

1129556

SMAG2
Protein Smaug homolog 2

2

0

High-throughput

0.316

High

236367

B4GT4
Beta-1,4-galactosyltransferase 4

1

0

High-throughput

0.279

Low

269321

SG2A1
Mammaglobin-B

1

0

High-throughput

0.279

Low

277249

TUSC2
Tumor suppressor candidate 2

1

0

High-throughput

0.279

Low

1081790

PROL4
Proline-rich protein 4

1

0

High-throughput

0.279

Low

1155899

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

1155900

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

1

0

High-throughput

0.279

Low

1155904

BPIB1
BPI fold-containing family B member 1

1

0

High-throughput

0.279

Low

1155909

TM169
Transmembrane protein 169

1

0

High-throughput

0.279

Low

1155913

PROL1
Opiorphin prepropeptide

1

0

High-throughput

0.279

Low

1155917

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.279

Low

1155910

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

0

High-throughput

0.269

Low

1155930

PPME1
Protein phosphatase methylesterase 1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024