HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 540
+	Hs
		651570 RFA1_HUMAN (1-616): 0: 781: 100.00		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		650764 RFA1_HUMAN (1-616): 0: 781: 100.00		SC24C_HUMAN (116-429): 9.64e-11: 66.7: 15.43
+	Hs
		651208 RFA1_HUMAN (1-616): 0: 781: 100.00		MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48
+	Hs
		651970 RFA1_HUMAN (1-616): 0: 781: 100.00		CHAP1_HUMAN (196-539): 2.7e-10: 65.2: 10.38
+	Hs
		652013 RFA1_HUMAN (1-616): 0: 781: 100.00		CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58
+	Hs
		651513 RFA1_HUMAN (1-616): 0: 781: 100.00		SRCAP_HUMAN (88-342): 3.17e-09: 62.1: 16.86
+	Hs
		651725 RFA1_HUMAN (1-616): 0: 781: 100.00		KMT2C_HUMAN (57-528): 6.72e-09: 61: 10.42
+	Hs
		1056865 RADX_HUMAN (27-384): 6.8e-66: 233: 16.24		MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48