HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: AURKB (Q96GD4)
Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)
Gene: AURKB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31586073, 37827155
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 344
+	Hs
		650467 RFA1_HUMAN (1-616): 0: 781: 100.00		AKT2_HUMAN (3-343): 1.2e-140: 408: 26.91
+	Hs
		650466 RFA1_HUMAN (1-616): 0: 781: 100.00		AKT1_HUMAN (3-343): 6.77e-137: 399: 28.53
+	Hs
		568552 RFA1_HUMAN (1-616): 0: 781: 100.00		KAPCA_HUMAN (36-342): 1.66e-134: 388: 26.18
+	Hs
		160393 RFA1_HUMAN (1-616): 0: 781: 100.00		AURKA_HUMAN (1-334): 2.45e-133: 387: 58.89
+	Zm
		2187 A0A1D6EZA2_MAIZE (83-505): 1.89e-78: 267: 14.57		A0A0B4J3D8_MAIZE (67-342): 3.26e-136: 396: 33.45