HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.705

Property	Details
Experiments	26474068, 24443570, 24332808, 28666352
Identification Methods	affinity chromatography technology, pull down, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0035861 - site of double-strand break
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 504
+	Hs
		651925 RFA1_HUMAN (1-616): 0: 781: 100.00		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		650859 RFA1_HUMAN (1-616): 0: 781: 100.00		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		652407 RFA1_HUMAN (1-616): 0: 781: 100.00		NLE1_HUMAN (93-333): 6.85e-38: 146: 14.86