HitPredict

Interactor 1: DDX6 (P23128)
ATP-dependent RNA helicase me31b (EC 3.6.4.13) (Maternal expression at 31B)
Gene: me31B

Interactor 2: IF4E (P48598)
Eukaryotic translation initiation factor 4E1 (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)
Gene: eIF4E1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

Property	Details
Experiments	14723848, 28875934, 35020877, 36638908
Identification Methods	affinity chromatography technology, proximity labelling technology, coimmunoprecipitation, two hybrid, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0005737 - cytoplasm GO:0071598 - neuronal ribonucleoprotein granule
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 459 Dm			1 259
+	Dm
		874938 DDX3_DROME (7-430): 6.43e-148: 442: 26.61		IF4E_DROME (1-259): 1.18e-148: 417: 100.00
+	Dm
		654388 DDX6_DROME (1-459): 2.46e-145: 424: 100.00		Q9VSG1_DROME (63-259): 3.31e-92: 273: 53.30
+	Hs
		141283 DDX3X_HUMAN (4-434): 1.01e-127: 386: 25.50		IF4E_HUMAN (67-259): 6.17e-102: 297: 50.26
+	Hs
		445495 DDX6_HUMAN (2-437): 7.64e-127: 378: 69.79		IF4E_HUMAN (67-259): 6.17e-102: 297: 50.26
+	Sc
		453949 DHH1_YEAST (31-436): 8.02e-131: 389: 68.47		IF4E_YEAST (48-249): 2.03e-72: 222: 37.56
+	Sc
		444390 DED1_YEAST (8-459): 4.86e-128: 385: 25.53		IF4E_YEAST (48-249): 2.03e-72: 222: 37.56
+	Dm
		90547 DDX6_DROME (1-459): 2.46e-145: 424: 100.00		C1C3I0_DROME (77-201): 4.14e-51: 166: 31.25
+	Sc
		453882 IF4A_YEAST (59-425): 1.32e-79: 254: 39.57		IF4E_YEAST (48-249): 2.03e-72: 222: 37.56