HitPredict

Interactor 1: PSB8 (P28062)
Proteasome subunit beta type-8 (EC 3.4.25.1) (Low molecular mass protein 7) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13) (Proteasome component C13) (Proteasome subunit beta-5i) (Really interesting new gene 10 protein)
Gene: PSMB8

Interactor 2: PSB6 (P28072)
Proteasome subunit beta type-6 (EC 3.4.25.1) (Macropain delta chain) (Multicatalytic endopeptidase complex delta chain) (Proteasome delta chain) (Proteasome subunit Y)
Gene: PSMB6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.849

The method score is based on:

Property Details
Experiments 11745344, 33961781, 17948026
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome
Common GO terms GO:0000502 - proteasome complex
GO:0004175 - endopeptidase activity
GO:0004298 - threonine-type endopeptidase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 5 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 276
Hs

1 239
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Last updated: 15 Jul 2024