HitPredict

Interactor 1: PSB9 (P28065)
Proteasome subunit beta type-9 (EC 3.4.25.1) (Low molecular mass protein 2) (Macropain chain 7) (Multicatalytic endopeptidase complex chain 7) (Proteasome chain 7) (Proteasome subunit beta-1i) (Really interesting new gene 12 protein)
Gene: PSMB9

Interactor 2: FBX7 (Q9Y3I1)
F-box only protein 7
Gene: FBXO7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 219 Hs			1 522
+	Hs
		656346 PSA5_HUMAN (5-219): 2.62e-78: 236: 17.90		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		656798 PSB5_HUMAN (2-219): 2.03e-73: 224: 27.15		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		1303500 PSB7_HUMAN (10-205): 6.35e-72: 221: 27.04		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		637761 PSA2_HUMAN (6-217): 4.83e-72: 220: 14.48		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		638222 PSA4_HUMAN (5-217): 2.38e-71: 219: 15.49		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		656663 PSB6_HUMAN (13-216): 4.09e-71: 218: 61.46		FBX7_HUMAN (1-522): 0: 1102: 100.00