HitPredict

Interactor 1: RS3 (P23396)
Small ribosomal subunit protein uS3 (40S ribosomal protein S3) (EC 4.2.99.18)
Gene: RPS3

Interactor 2: EIF2A (Q9BY44)
Eukaryotic translation initiation factor 2A (eIF-2A) (65 kDa eukaryotic translation initiation factor 2A) [Cleaved into: Eukaryotic translation initiation factor 2A, N-terminally processed]
Gene: EIF2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding GO:0005737 - cytoplasm GO:0006413 - translational initiation GO:0022627 - cytosolic small ribosomal subunit
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 585
+	Hs
		658057 RS3_HUMAN (1-243): 8.68e-116: 332: 100.00		EIF3B_HUMAN (14-517): 1.53e-87: 290: 17.53
+	Sc
		434679 RS3_YEAST (1-240): 1.7e-89: 266: 65.42		EIF3B_YEAST (14-500): 5.81e-101: 324: 15.37
+	Sc
		435242 RS3_YEAST (1-240): 1.7e-89: 266: 65.42		EIF2A_YEAST (8-581): 1.23e-88: 288: 25.54
+	Hs
		658367 RS3_HUMAN (1-243): 8.68e-116: 332: 100.00		PYM1_HUMAN (416-573): 5.44e-20: 90.3: 26.29
+	Hs
		658024 RS3_HUMAN (1-243): 8.68e-116: 332: 100.00		LIS1_HUMAN (310-529): 2.74e-16: 83.3: 13.51
+	Hs
		658375 RS3_HUMAN (1-243): 8.68e-116: 332: 100.00		KTNB1_HUMAN (2-141): 5.6e-15: 80.2: 11.27
+	Hs
		658072 RS3_HUMAN (1-243): 8.68e-116: 332: 100.00		WDR5_HUMAN (303-449): 6.86e-15: 77.9: 14.09
+	Hs
		658435 RS3_HUMAN (1-243): 8.68e-116: 332: 100.00		NLE1_HUMAN (355-490): 1.51e-10: 65.6: 8.09