Protein: PYM1
Partner of Y14 and mago (PYM homolog 1 exon junction complex-associated factor) (Protein wibg homolog)

Gene: PYM1
Organism: Homo sapiens
Interactions: 172
UniProt ID: Q9BRP8

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1411573

RBM8A
RNA-binding protein 8A

10

1

Small-scale

0.975

High

961101

MGN
Protein mago nashi homolog

10

2

Small-scale

0.973

High

1382621

MGN2
Protein mago nashi homolog 2

2

2

High-throughput

0.737

High

1359794

RT4I1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial

4

1

High-throughput

0.626

High

396828

ESR1
Estrogen receptor

3

0

High-throughput

0.606

High

183504

CASC3
Protein CASC3

2

0

High-throughput

0.602

High

709003

T2EB
Transcription initiation factor IIE subunit beta

2

0

High-throughput

0.602

High

733857

CDD
Cytidine deaminase

2

0

High-throughput

0.602

High

842986

CDN2C
Cyclin-dependent kinase 4 inhibitor C

2

0

High-throughput

0.602

High

1099766

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

0

High-throughput

0.602

High

1136755

MD2BP
MAD2L1-binding protein

2

0

High-throughput

0.602

High

1395140

DCAF5
DDB1- and CUL4-associated factor 5

2

0

High-throughput

0.602

High

473027

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.586

High

1096193

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.586

High

530299

TAU
Microtubule-associated protein tau

2

0

High-throughput

0.576

High

970068

RS16
Small ribosomal subunit protein uS9

2

0

High-throughput

0.576

High

1194336

LARP7
La-related protein 7

1

2

High-throughput

0.575

High

1383036

LRC59
Leucine-rich repeat-containing protein 59

2

0

High-throughput

0.559

High

1411555

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.549

High

175769

SR140
U2 snRNP-associated SURP motif-containing protein

1

0

High-throughput

0.546

High

1148772

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

0

High-throughput

0.546

High

1178705

MTHSD
Methenyltetrahydrofolate synthase domain-containing protein

1

0

High-throughput

0.546

High

1411538

RBM42
RNA-binding protein 42

1

0

High-throughput

0.546

High

1411540

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

0

High-throughput

0.546

High

1411571

RBM19
Probable RNA-binding protein 19

1

0

High-throughput

0.546

High

1136334

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.536

High

245267

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

0

High-throughput

0.513

High

332438

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

1

0

High-throughput

0.513

High

606070

KCNA6
Potassium voltage-gated channel subfamily A member 6

1

0

High-throughput

0.513

High

611963

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

787701

SPB5
Serpin B5

1

0

High-throughput

0.513

High

1273125

MOB1B
MOB kinase activator 1B

1

0

High-throughput

0.513

High

1366542

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.513

High

1366806

PGTA
Geranylgeranyl transferase type-2 subunit alpha

1

0

High-throughput

0.513

High

1402549

SRPK1
SRSF protein kinase 1

1

0

High-throughput

0.513

High

1411546

NELFA
Negative elongation factor A

1

0

High-throughput

0.513

High

1411565

KLH20
Kelch-like protein 20

1

0

High-throughput

0.513

High

861750

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

1

High-throughput

0.501

High

1399999

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

1

High-throughput

0.501

High

1358255

ANR49
Ankyrin repeat domain-containing protein 49

1

1

High-throughput

0.489

High

404891

PRIO
Major prion protein

1

0

Small-scale

0.480

High

423000

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1209579

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.480

High

173288

XPO1
Exportin-1

1

2

High-throughput

0.479

High

298441

DNJC8
DnaJ homolog subfamily C member 8

1

1

High-throughput

0.479

High

346255

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

372996

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

406571

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

1050524

UBE3A
Ubiquitin-protein ligase E3A

1

2

High-throughput

0.479

High

1087685

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

1

High-throughput

0.479

High

1215796

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

1255281

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1370659

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

1

High-throughput

0.479

High

1405129

DNJC2
DnaJ homolog subfamily C member 2

1

1

High-throughput

0.479

High

1411552

RC3H2
Roquin-2

1

1

High-throughput

0.479

High

1411560

XPO7
Exportin-7

1

2

High-throughput

0.479

High

73673

B2R9Y1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial

1

1

High-throughput

0.470

High

260378

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

352532

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

401392

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

425615

ISG15
Ubiquitin-like protein ISG15

1

0

High-throughput

0.458

High

447848

TPM3
Tropomyosin alpha-3 chain

1

0

High-throughput

0.458

High

718618

CDC27
Cell division cycle protein 27 homolog

1

0

Small-scale

0.458

High

772200

MSX2
Homeobox protein MSX-2

1

0

High-throughput

0.458

High

872688

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

970991

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

982794

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

1024804

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1067658

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1089261

TRI26
Tripartite motif-containing protein 26

1

0

Small-scale

0.458

High

1126524

CAPR1
Caprin-1

1

0

High-throughput

0.458

High

1137492

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1138567

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1155711

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1156841

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1280304

DNJB7
DnaJ homolog subfamily B member 7

1

0

High-throughput

0.458

High

1289584

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1364560

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1411558

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1411563

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

599869

YBOX3
Y-box-binding protein 3

1

2

High-throughput

0.445

High

994757

YBOX1
Y-box-binding protein 1

1

2

Small-scale

0.445

High

1240484

DHX57
Putative ATP-dependent RNA helicase DHX57

1

2

High-throughput

0.445

High

1259144

LARP4
La-related protein 4

1

1

High-throughput

0.445

High

1272052

ZN771
Zinc finger protein 771

1

1

High-throughput

0.445

High

1313918

DHX37
Probable ATP-dependent RNA helicase DHX37

1

1

High-throughput

0.445

High

1402763

STRBP
Spermatid perinuclear RNA-binding protein

1

1

High-throughput

0.445

High

1411536

UTP23
rRNA-processing protein UTP23 homolog

1

1

High-throughput

0.445

High

1411541

YTHD1
YTH domain-containing family protein 1

1

1

High-throughput

0.445

High

1411545

E41LB
Band 4.1-like protein 4B

1

1

High-throughput

0.445

High

1411549

YTDC2
3'-5' RNA helicase YTHDC2

1

1

High-throughput

0.445

High

1411553

E41L5
Band 4.1-like protein 5

1

1

High-throughput

0.445

High

1411561

BAZ1B
Tyrosine-protein kinase BAZ1B

1

2

High-throughput

0.445

High

1411566

YBOX2
Y-box-binding protein 2

1

2

High-throughput

0.445

High

1411567

FCF1
rRNA-processing protein FCF1 homolog

1

1

High-throughput

0.445

High

1411572

MAFB
Transcription factor MafB

1

1

High-throughput

0.437

High

134368

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.426

High

138399

ZN593
Zinc finger protein 593

1

0

High-throughput

0.426

High

140626

MPP10
U3 small nucleolar ribonucleoprotein protein MPP10

1

0

High-throughput

0.426

High

182353

WDR46
WD repeat-containing protein 46

1

0

High-throughput

0.426

High

243719

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

0

High-throughput

0.426

High

340527

ZBT11
Zinc finger and BTB domain-containing protein 11

1

0

High-throughput

0.426

High

354765

PAK4
Serine/threonine-protein kinase PAK 4

1

0

High-throughput

0.426

High

430294

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

475430

RS17
Small ribosomal subunit protein eS17

1

0

High-throughput

0.426

High

586858

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.426

High

658367

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.426

High

807557

IF4A3
Eukaryotic initiation factor 4A-III

1

0

High-throughput

0.426

High

809812

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.426

High

860596

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.426

High

860915

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.426

High

959930

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.426

High

969396

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.426

High

977351

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.426

High

979182

RS6
Small ribosomal subunit protein eS6

1

0

Small-scale

0.426

High

981943

RL23
Large ribosomal subunit protein uL14

1

0

Small-scale

0.426

High

982533

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.426

High

984940

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.426

High

1004392

NOP14
Nucleolar protein 14

1

0

High-throughput

0.426

High

1016188

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.426

High

1032859

XPC
DNA repair protein complementing XP-C cells

1

0

High-throughput

0.426

High

1085699

TBL3
Transducin beta-like protein 3

1

0

High-throughput

0.426

High

1117648

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.426

High

1179359

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

0

High-throughput

0.426

High

1193371

GLYR1
Cytokine-like nuclear factor N-PAC

1

0

High-throughput

0.426

High

1198646

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

1208800

TDIF2
Deoxynucleotidyltransferase terminal-interacting protein 2

1

0

High-throughput

0.426

High

1219426

TUT7
Terminal uridylyltransferase 7

1

0

High-throughput

0.426

High

1234504

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.426

High

1247573

F111B
Serine protease FAM111B

1

0

High-throughput

0.426

High

1308432

ERI1
3'-5' exoribonuclease 1

1

0

High-throughput

0.426

High

1327376

ZCHC9
Zinc finger CCHC domain-containing protein 9

1

0

High-throughput

0.426

High

1328342

ZC3H8
Zinc finger CCCH domain-containing protein 8

1

0

High-throughput

0.426

High

1337412

SRFB1
Serum response factor-binding protein 1

1

0

High-throughput

0.426

High

1337482

NGDN
Neuroguidin

1

0

High-throughput

0.426

High

1357538

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.426

High

1358274

TFB1M
Dimethyladenosine transferase 1, mitochondrial

1

0

High-throughput

0.426

High

1384681

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.426

High

1403645

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

0

High-throughput

0.426

High

1407153

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

0

High-throughput

0.426

High

1411537

TRI56
E3 ubiquitin-protein ligase TRIM56

1

0

High-throughput

0.426

High

1411542

HELZ2
3'-5' exoribonuclease HELZ2

1

0

High-throughput

0.426

High

1411548

ZN768
Zinc finger protein 768

1

0

High-throughput

0.426

High

1411551

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.426

High

1411556

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.426

High

1411557

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.426

High

1411559

NOL12
Nucleolar protein 12

1

0

High-throughput

0.426

High

1411562

ZN346
Zinc finger protein 346

1

0

High-throughput

0.426

High

1411564

RL26L
Ribosomal protein uL24-like

1

0

High-throughput

0.426

High

1411568

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.426

High

1411569

RRP7A
Ribosomal RNA-processing protein 7 homolog A

1

0

High-throughput

0.426

High

1411570

NOP16
Nucleolar protein 16

1

0

High-throughput

0.426

High

387883

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

0

High-throughput

0.328

High

665686

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.279

Low

1389106

KBP
KIF-binding protein

1

0

High-throughput

0.279

Low

1411539

MND1
Meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.279

Low

1411544

S2532
Solute carrier family 25 member 32

1

0

High-throughput

0.279

Low

1411547

GSX1
GS homeobox 1

1

0

High-throughput

0.279

Low

106563

APRIO
Alternative prion protein

1

0

Small-scale

0.261

Low

1226507

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

1327160

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1388253

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.249

Low

1153663

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

1

0

High-throughput

0.232

Low

1203518

S45A4
Solute carrier family 45 member 4

1

0

High-throughput

0.232

Low

1219044

RSBN1
Lysine-specific demethylase 9

1

0

High-throughput

0.232

Low

1251489

S36A4
Neutral amino acid uniporter 4

1

0

High-throughput

0.232

Low

1252661

ZN574
Zinc finger protein 574

1

0

High-throughput

0.232

Low

1259245

NCKX5
Sodium/potassium/calcium exchanger 5

1

0

High-throughput

0.232

Low

1353692

ZN384
Zinc finger protein 384

1

0

High-throughput

0.232

Low

1411543

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.232

Low

1411550

CH033
UPF0488 protein C8orf33

1

0

High-throughput

0.232

Low

1411554

PRD10
PR domain zinc finger protein 10

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025