HitPredict

Interactor 1: WNT2 (P28465)
Protein Wnt-2 (dWnt-2)
Gene: WNT2

Interactor 2: WLS (Q95ST2)
Protein wntless (Evenness interrupted) (Sprinter)
Gene: WLS

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22108505
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	MIG-14_Wnt-bd~wnt
Common GO terms	GO:0007367 - segment polarity determination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 352 Dm			1 594
+	Mm
		568285 WNT3_MOUSE (6-352): 1.01e-161: 457: 45.58		WLS_MOUSE (1-585): 0: 790: 40.65
+	Dm
		776060 WNT4_DROME (30-352): 2.89e-107: 325: 31.80		WLS_DROME (1-594): 0: 914: 100.00
+	Hs
		881860 WNT3A_HUMAN (4-352): 6.3e-159: 451: 44.48		WLS_HUMAN (1-585): 0: 785: 40.82
+	Dm
		1279554 Q9VM25_DROME (20-335): 1.52e-102: 312: 30.92		WLS_DROME (1-594): 0: 914: 100.00
+	Hs
		135861 WNT7A_HUMAN (13-352): 1.09e-152: 434: 48.53		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		881899 WNT7B_HUMAN (18-352): 2.78e-152: 434: 48.96		WLS_HUMAN (1-585): 0: 785: 40.82
+	Mm
		611175 WNT5A_MOUSE (16-352): 1.01e-145: 418: 40.00		WLS_MOUSE (1-585): 0: 790: 40.65
+	Hs
		782089 WNT5A_HUMAN (16-352): 9.81e-146: 418: 40.00		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		881881 WNT4_HUMAN (13-352): 2.57e-145: 416: 38.48		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		1135438 WNT5B_HUMAN (16-352): 8.33e-144: 412: 39.71		WLS_HUMAN (1-585): 0: 785: 40.82
+	Mm
		382254 WNT1_MOUSE (32-351): 7.67e-140: 403: 38.13		WLS_MOUSE (1-585): 0: 790: 40.65
+	Hs
		451998 WNT2_HUMAN (24-352): 3.58e-142: 408: 41.99		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		384072 WNT1_HUMAN (32-351): 8.28e-140: 402: 38.13		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		1135451 WNT16_HUMAN (30-352): 3.19e-131: 380: 38.58		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		1135437 WNT8A_HUMAN (53-351): 4.34e-125: 365: 39.54		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		158076 WNT9B_HUMAN (30-352): 4.43e-121: 355: 34.99		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		158068 WNT9A_HUMAN (30-352): 1.59e-117: 346: 36.22		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		1135420 WNT8B_HUMAN (53-351): 5.27e-113: 334: 36.60		WLS_HUMAN (1-585): 0: 785: 40.82
+	Dm
		658776 WNT5_DROME (30-175): 3.06e-49: 179: 30.82		WLS_DROME (1-594): 0: 914: 100.00
+	Dm
		452324 WNTG_DROME (256-351): 3.67e-38: 143: 40.63		WLS_DROME (1-594): 0: 914: 100.00