Interactor 1: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Interactor 2: IEX1 (P46695)
Radiation-inducible immediate-early gene IEX-1 (Differentiation-dependent gene 2 protein) (Protein DIF-2) (Immediate early protein GLY96) (Immediate early response 3 protein) (PACAP-responsive gene 1 protein) (Protein PRG1)
Gene: IER3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.649

The method score is based on:

Property Details
Experiments 12356731, 16456541
Identification Methods enzymatic study, pull down, protein kinase assay
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0006974 - DNA damage response
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 360
Hs

1 156
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024