Interactor 1: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 20974803, 16517408, 18296712
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PB1~Pkinase
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005770 - late endosome
GO:0005829 - cytosol
and 2 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 360
Hs

1 440
+ Hs
+ Mm
+ Mm
+ Hs
+ Ce
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024