HitPredict

Interactor 1: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Interactor 2: DUS19 (Q8WTR2)
Dual specificity protein phosphatase 19 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase TS-DSP1) (Low molecular weight dual specificity phosphatase 3) (LMW-DSP3) (Protein phosphatase SKRP1) (Stress-activated protein kinase pathway-regulating phosphatase 1) (SAPK pathway-regulating phosphatase 1)
Gene: DUSP19

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27432908
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DSPc~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 360 Hs			1 217
+	Hs
		658798 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		DUS1_HUMAN (18-217): 1.18e-74: 231: 29.85
+	Hs
		647475 MK03_HUMAN (4-358): 3.09e-154: 440: 85.92		DUS1_HUMAN (18-217): 1.18e-74: 231: 29.85
+	Hs
		658919 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		DUS4_HUMAN (47-217): 3.09e-69: 218: 33.92
+	Hs
		658960 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		DUS5_HUMAN (18-217): 6.31e-66: 209: 27.54
+	Hs
		659034 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		DUS9_HUMAN (38-216): 1.19e-65: 209: 31.38
+	Hs
		658962 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		DUS7_HUMAN (34-215): 4.58e-65: 208: 32.97
+	Hs
		658903 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		DUS2_HUMAN (59-205): 1.16e-64: 204: 36.74
+	Mm
		926403 MK01_MOUSE (10-360): 4.96e-158: 449: 99.72		DUS2_MOUSE (28-205): 2.96e-64: 203: 31.32
+	Hs
		647553 MK03_HUMAN (4-358): 3.09e-154: 440: 85.92		DUS2_HUMAN (59-205): 1.16e-64: 204: 36.74
+	Mm
		926439 MK01_MOUSE (10-360): 4.96e-158: 449: 99.72		DUS6_MOUSE (47-216): 1.78e-60: 195: 32.95
+	Hs
		659043 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		DUS16_HUMAN (42-207): 1.48e-57: 194: 28.14
+	Hs
		658961 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		DUS6_HUMAN (47-214): 8.49e-60: 193: 33.33
+	Rn
		926496 MK01_RAT (10-360): 4.96e-158: 449: 99.72		DUS6_RAT (47-214): 8.49e-60: 193: 33.33
+	Hs
		658923 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		DUS8_HUMAN (45-204): 1.03e-56: 191: 30.06
+	Hs
		659008 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		STYX_HUMAN (42-215): 5.73e-57: 181: 29.83
+	Hs
		659081 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		DS13B_HUMAN (56-204): 5.54e-53: 170: 31.85
+	Hs
		659090 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		DUS12_HUMAN (48-201): 1.46e-19: 87: 33.13
+	Hs
		658858 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		DUS3_HUMAN (69-204): 5.64e-20: 85.1: 35.95
+	Mm
		926438 MK01_MOUSE (10-360): 4.96e-158: 449: 99.72		DUS3_MOUSE (69-204): 3.59e-19: 83.2: 36.42
+	Hs
		647521 MK03_HUMAN (4-358): 3.09e-154: 440: 85.92		DUS3_HUMAN (69-204): 5.64e-20: 85.1: 35.95