HitPredict

Interactor 1: IF4B (P23588)
Eukaryotic translation initiation factor 4B (eIF-4B)
Gene: EIF4B

Interactor 2: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	17361185
Identification Methods	far western blotting, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 611 Hs			1 248
+	Hs
		660581 IF4B_HUMAN (1-611): 5.66e-98: 313: 100.00		1433E_HUMAN (2-246): 4.43e-146: 410: 60.41
+	Hs
		660598 IF4B_HUMAN (1-611): 5.66e-98: 313: 100.00		1433Z_HUMAN (1-242): 8.34e-142: 398: 70.66
+	Hs
		660530 IF4B_HUMAN (1-611): 5.66e-98: 313: 100.00		1433T_HUMAN (1-238): 1e-107: 312: 71.85
+	Hs
		660534 IF4B_HUMAN (1-611): 5.66e-98: 313: 100.00		1433B_HUMAN (1-239): 3.42e-100: 293: 68.62
+	Hs
		660574 IF4B_HUMAN (1-611): 5.66e-98: 313: 100.00		1433G_HUMAN (1-242): 1.87e-98: 289: 65.16
+	Hs
		660610 IF4B_HUMAN (1-611): 5.66e-98: 313: 100.00		1433F_HUMAN (2-242): 2.79e-96: 283: 64.20
+	Hs
		550138 PABP1_HUMAN (49-545): 1.61e-25: 113: 10.58		1433S_HUMAN (1-248): 3.5e-158: 440: 100.00
+	Hs
		550210 PABP1_HUMAN (49-545): 1.61e-25: 113: 10.58		1433E_HUMAN (2-246): 4.43e-146: 410: 60.41
+	Hs
		971478 PABP4_HUMAN (49-389): 2.91e-22: 103: 9.72		1433E_HUMAN (2-246): 4.43e-146: 410: 60.41
+	Hs
		971405 RBM3_HUMAN (98-241): 2.32e-22: 95.7: 24.83		1433E_HUMAN (2-246): 4.43e-146: 410: 60.41
+	Hs
		990180 PABP4_HUMAN (49-389): 2.91e-22: 103: 9.72		1433Z_HUMAN (1-242): 8.34e-142: 398: 70.66
+	Hs
		690972 PABP4_HUMAN (49-389): 2.91e-22: 103: 9.72		1433T_HUMAN (1-238): 1e-107: 312: 71.85
+	Hs
		550206 PABP1_HUMAN (49-545): 1.61e-25: 113: 10.58		1433G_HUMAN (1-242): 1.87e-98: 289: 65.16
+	Mm
		953824 CIRBP_MOUSE (98-257): 3.97e-30: 118: 23.03		1433F_MOUSE (2-242): 1.73e-96: 284: 64.20
+	Hs
		729802 PABP4_HUMAN (49-389): 2.91e-22: 103: 9.72		1433B_HUMAN (1-239): 3.42e-100: 293: 68.62