HitPredict

Interactor 1: PTPRM (P28827)
Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48)
Gene: PTPRM

Interactor 2: PTPRM (P28827)
Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48)
Gene: PTPRM

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.745

The method score is based on:

Property Details
Experiments 10809770, 15978577
Identification Methods two hybrid, anti tag coimmunoprecipitation, tox-r dimerization assay
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains fn3~fn3, fn3~ig, ig~ig, MAM~ig, MAM~MAM, Y_phosphatase~Y_phosphatase
Common GO terms GO:0001937 - negative regulation of endothelial cell proliferation
GO:0004725 - protein tyrosine phosphatase activity
GO:0005001 - transmembrane receptor protein tyrosine phosphatase activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
and 15 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024