HitPredict

Interactor 1: TNR8 (P28908)
Tumor necrosis factor receptor superfamily member 8 (CD30L receptor) (Ki-1 antigen) (Lymphocyte activation antigen CD30) (CD antigen CD30)
Gene: TNFRSF8

Interactor 2: TRAF1 (Q13077)
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene: TRAF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Property	Details
Experiments	28514442, 33961781, 8662842, 9168896
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 416
+	Hs
		661043 TNR8_HUMAN (1-595): 0: 570: 100.00		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		591319 TNR1B_HUMAN (12-239): 1.19e-49: 180: 26.16		TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00
+	Hs
		1023848 TNR11_HUMAN (30-202): 4.53e-45: 170: 22.10		TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00
+	Hs
		129534 TNR8_HUMAN (1-595): 0: 570: 100.00		TRAF5_HUMAN (14-261): 1.36e-16: 83.8: 13.91
+	Hs
		436619 TNR16_HUMAN (29-243): 1.87e-43: 162: 19.82		TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00
+	Hs
		661045 TNR8_HUMAN (1-595): 0: 570: 100.00		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77
+	Hs
		591317 TNR1B_HUMAN (12-239): 1.19e-49: 180: 26.16		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Mm
		761805 TNR3_MOUSE (13-226): 6.17e-46: 169: 21.33		TRAF2_MOUSE (3-415): 3.91e-127: 378: 37.77
+	Hs
		1021008 TNR11_HUMAN (30-202): 4.53e-45: 170: 22.10		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		436618 TNR16_HUMAN (29-243): 1.87e-43: 162: 19.82		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		591438 TNR1B_HUMAN (12-239): 1.19e-49: 180: 26.16		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Hs
		1377881 TNR11_HUMAN (30-202): 4.53e-45: 170: 22.10		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Hs
		129607 TNR11_HUMAN (30-202): 4.53e-45: 170: 22.10		TRAF5_HUMAN (14-261): 1.36e-16: 83.8: 13.91
+	Hs
		129526 TNR16_HUMAN (29-243): 1.87e-43: 162: 19.82		TRAF5_HUMAN (14-261): 1.36e-16: 83.8: 13.91
+	Hs
		591320 TNR1B_HUMAN (12-239): 1.19e-49: 180: 26.16		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77
+	Mm
		838552 TNR3_MOUSE (13-226): 6.17e-46: 169: 21.33		TRAF5_MOUSE (14-296): 7.86e-13: 71.9: 13.45
+	Mm
		838553 TNR3_MOUSE (13-226): 6.17e-46: 169: 21.33		TRAF3_MOUSE (1-262): 2.34e-12: 70.7: 16.37
+	Hs
		1024798 TNR11_HUMAN (30-202): 4.53e-45: 170: 22.10		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77
+	Hs
		436620 TNR16_HUMAN (29-243): 1.87e-43: 162: 19.82		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77
+	Hs
		436641 TNR16_HUMAN (29-243): 1.87e-43: 162: 19.82		TRAF4_HUMAN (27-136): 3.55e-09: 60.3: 17.86