Protein: GRIP1
Glutamate receptor-interacting protein 1 (GRIP-1)

Gene: GRIP1
Organism: Homo sapiens
Interactions: 94
UniProt ID: Q9Y3R0

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008013 - beta-catenin binding
GO:0014069 - postsynaptic density

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1491269

GRIP1
Glutamate receptor-interacting protein 1

2

16

Small-scale

0.826

High

1404715

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

18

Small-scale

0.740

High

730388

1433B
14-3-3 protein beta/alpha

6

20

High-throughput

0.730

High

838517

GRIA2
Glutamate receptor 2

5

20

Small-scale

0.707

High

1104900

SNTB2
Beta-2-syntrophin

1

20

High-throughput

0.691

High

691573

1433T
14-3-3 protein theta

4

20

High-throughput

0.678

High

967060

1433G
14-3-3 protein gamma

3

20

High-throughput

0.669

High

1049939

1433F
14-3-3 protein eta

3

20

High-throughput

0.667

High

397297

ESR1
Estrogen receptor

3

20

Small-scale

0.658

High

1293438

CARM1
Histone-arginine methyltransferase CARM1

3

2

Small-scale

0.650

High

881751

FNTB
Protein farnesyltransferase subunit beta

3

0

High-throughput

0.638

High

972168

1433E
14-3-3 protein epsilon

2

5

High-throughput

0.621

High

710588

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

1420551

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

20

Small-scale

0.618

High

1448404

PICK1
PRKCA-binding protein

1

4

Small-scale

0.618

High

533312

THA
Thyroid hormone receptor alpha

2

14

Small-scale

0.614

High

789602

PPARG
Peroxisome proliferator-activated receptor gamma

2

20

Small-scale

0.614

High

1067869

EP300
Histone acetyltransferase p300

2

4

Small-scale

0.614

High

1438802

NEK6
Serine/threonine-protein kinase Nek6

2

4

High-throughput

0.606

High

1445758

WDR6
tRNA

2

4

High-throughput

0.606

High

1208606

SMAG2
Protein Smaug homolog 2

1

0

High-throughput

0.586

High

404565

GCR
Glucocorticoid receptor

2

20

Small-scale

0.584

High

261743

HUS1
Checkpoint protein HUS1

2

0

High-throughput

0.580

High

869292

XDH
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase

2

0

High-throughput

0.580

High

935706

MFAP3
Microfibril-associated glycoprotein 3

2

0

High-throughput

0.580

High

1273114

EEPD1
Endonuclease/exonuclease/phosphatase family domain-containing protein 1

2

0

High-throughput

0.580

High

1491271

NUMBL
Numb-like protein

1

17

Small-scale

0.555

High

1256225

TRI67
Tripartite motif-containing protein 67

1

20

Small-scale

0.553

High

1196347

GRAP1
GRIP1-associated protein 1

1

7

Small-scale

0.552

High

900240

FXR1
RNA-binding protein FXR1

1

16

High-throughput

0.541

High

900567

FXR2
RNA-binding protein FXR2

1

16

High-throughput

0.541

High

833599

UBA7
Ubiquitin-like modifier-activating enzyme 7

1

1

High-throughput

0.536

High

1116166

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

8

High-throughput

0.536

High

700551

PSB9
Proteasome subunit beta type-9

1

1

Small-scale

0.529

High

838540

GRIA3
Glutamate receptor 3

1

20

Small-scale

0.527

High

870113

GRIA4
Glutamate receptor 4

1

20

Small-scale

0.527

High

993825

UBC9
SUMO-conjugating enzyme UBC9

1

5

Small-scale

0.527

High

1132685

GRM7
Metabotropic glutamate receptor 7

1

18

Small-scale

0.527

High

1132689

GRM3
Metabotropic glutamate receptor 3

1

14

Small-scale

0.527

High

730981

1433S
14-3-3 protein sigma

1

20

High-throughput

0.515

High

886162

PRLHR
Prolactin-releasing peptide receptor

1

20

Small-scale

0.515

High

1294599

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

7

Small-scale

0.512

High

1420084

KPCD2
Serine/threonine-protein kinase D2

1

15

High-throughput

0.508

High

1129200

IRF3
Interferon regulatory factor 3

1

2

Small-scale

0.506

High

1194055

KMT5B
Histone-lysine N-methyltransferase KMT5B

1

0

Small-scale

0.504

High

543554

VDR
Vitamin D3 receptor

1

17

Small-scale

0.501

High

625852

RXRA
Retinoic acid receptor RXR-alpha

1

18

Small-scale

0.501

High

811302

GRIK1
Glutamate receptor ionotropic, kainate 1

1

20

Small-scale

0.501

High

838474

GRIA1
Glutamate receptor 1

1

20

Small-scale

0.501

High

914564

EFNA5
Ephrin-A5

1

5

Small-scale

0.501

High

1092408

GRIK2
Glutamate receptor ionotropic, kainate 2

1

20

Small-scale

0.501

High

1093339

FLII
Protein flightless-1 homolog

1

7

Small-scale

0.501

High

1126223

GRM2
Metabotropic glutamate receptor 2

1

18

Small-scale

0.501

High

1130612

NCOA6
Nuclear receptor coactivator 6

1

2

Small-scale

0.501

High

1407971

ANM1
Protein arginine N-methyltransferase 1

1

2

Small-scale

0.501

High

186955

GPR37
Prosaposin receptor GPR37

1

16

Small-scale

0.481

High

336808

BAG4
BAG family molecular chaperone regulator 4

1

2

High-throughput

0.481

High

520477

ANDR
Androgen receptor

1

20

Small-scale

0.481

High

1248247

CSPG4
Chondroitin sulfate proteoglycan 4

1

15

Small-scale

0.481

High

1357450

DEP1B
DEP domain-containing protein 1B

1

9

Small-scale

0.481

High

530646

TAU
Microtubule-associated protein tau

1

8

High-throughput

0.479

High

643156

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

20

High-throughput

0.479

High

648751

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.479

High

765147

CTNB1
Catenin beta-1

1

19

Small-scale

0.479

High

791866

SYUA
Alpha-synuclein

1

8

High-throughput

0.479

High

990908

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1014673

SMAD3
Mothers against decapentaplegic homolog 3

1

2

Small-scale

0.479

High

1110213

HDAC1
Histone deacetylase 1

1

7

Small-scale

0.479

High

1114728

CUL3
Cullin-3

1

9

High-throughput

0.479

High

1226333

CP135
Centrosomal protein of 135 kDa

1

6

High-throughput

0.479

High

1259595

TBA1A
Tubulin alpha-1A chain

1

13

High-throughput

0.479

High

1339772

TNIP2
TNFAIP3-interacting protein 2

1

2

High-throughput

0.479

High

1368536

CBP
CREB-binding protein

1

2

Small-scale

0.479

High

1400203

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

20

High-throughput

0.479

High

1409568

B9D2
B9 domain-containing protein 2

1

1

High-throughput

0.479

High

1428797

SRR
Serine racemase

1

1

Small-scale

0.479

High

1448725

LATS2
Serine/threonine-protein kinase LATS2

1

20

High-throughput

0.479

High

210367

PHF1
PHD finger protein 1

1

0

Small-scale

0.458

High

1491270

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

0

High-throughput

0.458

High

1156249

ZYX
Zyxin

1

17

Small-scale

0.457

High

279586

LAT3
Large neutral amino acids transporter small subunit 3

1

2

High-throughput

0.445

High

827284

ARL1
ADP-ribosylation factor-like protein 1

1

8

Small-scale

0.445

High

1258630

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

4

High-throughput

0.445

High

1153798

NCOA1
Nuclear receptor coactivator 1

1

0

Small-scale

0.438

High

455670

KLK3
Prostate-specific antigen

1

1

Small-scale

0.437

High

1352290

DCA11
DDB1- and CUL4-associated factor 11

1

4

High-throughput

0.437

High

1382014

CK052
Uncharacterized protein C11orf52

1

7

High-throughput

0.437

High

1396331

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

19

Small-scale

0.437

High

1430468

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.426

High

1225120

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

18

Small-scale

0.407

High

961236

FGF12
Fibroblast growth factor 12

2

0

High-throughput

0.316

High

998992

H31
Histone H3.1

1

0

Small-scale

0.261

Low

219395

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025