HitPredict - High confidence protein-protein interactions

Interactor 1: SPT6 (P23615)
Transcription elongation factor SPT6 (Chromatin elongation factor SPT6)
Gene: SPT6

Interactor 2: SPT6 (P23615)
Transcription elongation factor SPT6 (Chromatin elongation factor SPT6)
Gene: SPT6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.755

Property	Details
Experiments	35640611, 21179020
Identification Methods	pull down, tandem affinity purification
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	HHH_7~HTH_44, HHH_7~Tex_central_region, HHH_7~YqgF, HTH_44~Tex_central_region, SH2_2~SH2_2, SH2_2~Spt6_S1, Spt6_S1~YqgF
Common GO terms	GO:0000082 - G1/S transition of mitotic cell cycle GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000791 - euchromatin GO:0001073 - transcription antitermination factor activity, DNA binding GO:0003677 - DNA binding and 16 others more... GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0006334 - nucleosome assembly GO:0006338 - chromatin remodeling GO:0006366 - transcription by RNA polymerase II GO:0006368 - transcription elongation by RNA polymerase II GO:0008023 - transcription elongation factor complex GO:0016973 - poly(A)+ mRNA export from nucleus GO:0031440 - regulation of mRNA 3'-end processing GO:0031491 - nucleosome binding GO:0031564 - transcription antitermination GO:0032968 - positive regulation of transcription elongation by RNA polymerase II GO:0033554 - cellular response to stress GO:0034728 - nucleosome organization GO:0042393 - histone binding GO:0140673 - transcription elongation-coupled chromatin remodeling
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1	1451
Sc

1	1451

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Last updated: 11Aug2025