HitPredict

Interactor 1: S10A2 (P29034)
Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)
Gene: S100A2

Interactor 2: SHPRH (Q149N8)
E3 ubiquitin-protein ligase SHPRH (EC 2.3.2.27) (EC 3.6.4.-) (RING-type E3 ubiquitin transferase SHPRH) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)
Gene: SHPRH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 98 Hs			1 1683
+	Hs
		638958 S100P_HUMAN (4-92): 8.31e-36: 118: 42.70		SHPRH_HUMAN (1-1683): 0: 1247: 100.00
+	Hs
		1018566 HORN_HUMAN (2-90): 2.84e-32: 119: 28.09		CHD3_HUMAN (1279-1682): 6.88e-103: 368: 17.87
+	Hs
		1018521 FILA2_HUMAN (4-91): 2.11e-27: 105: 32.96		CHD3_HUMAN (1279-1682): 6.88e-103: 368: 17.87
+	Hs
		416414 S10A9_HUMAN (4-98): 1.67e-30: 105: 32.29		CHD3_HUMAN (1279-1682): 6.88e-103: 368: 17.87
+	Hs
		396727 S10A8_HUMAN (2-89): 6.86e-27: 96.1: 29.55		CHD3_HUMAN (1279-1682): 6.88e-103: 368: 17.87
+	Hs
		1059716 HORN_HUMAN (2-90): 2.84e-32: 119: 28.09		CHD4_HUMAN (1275-1682): 1.8e-95: 345: 17.70
+	Hs
		1059662 FILA2_HUMAN (4-91): 2.11e-27: 105: 32.96		CHD4_HUMAN (1275-1682): 1.8e-95: 345: 17.70
+	Hs
		416427 S10A9_HUMAN (4-98): 1.67e-30: 105: 32.29		CHD4_HUMAN (1275-1682): 1.8e-95: 345: 17.70
+	Hs
		396737 S10A8_HUMAN (2-89): 6.86e-27: 96.1: 29.55		CHD4_HUMAN (1275-1682): 1.8e-95: 345: 17.70
+	Hs
		596279 FILA_HUMAN (2-90): 2.02e-21: 88.7: 25.84		CHD4_HUMAN (1275-1682): 1.8e-95: 345: 17.70
+	Hs
		678449 S10A7_HUMAN (1-93): 1.64e-21: 82.6: 22.11		CHD4_HUMAN (1275-1682): 1.8e-95: 345: 17.70
+	Hs
		380880 S100B_HUMAN (4-92): 8.65e-33: 111: 44.94		TTF2_HUMAN (1507-1675): 3.08e-52: 204: 27.75
+	Hs
		661458 S10A2_HUMAN (1-98): 9.73e-40: 128: 100.00		HELLS_HUMAN (689-1006): 1.51e-25: 117: 15.67
+	Hs
		639095 S100P_HUMAN (4-92): 8.31e-36: 118: 42.70		HELLS_HUMAN (689-1006): 1.51e-25: 117: 15.67
+	Mm
		437546 S10AA_MOUSE (2-91): 6.19e-34: 114: 34.44		HLTF_MOUSE (272-390): 1.67e-10: 68.2: 30.25
+	Hs
		893794 S10AA_HUMAN (2-91): 2.43e-33: 112: 36.67		HLTF_HUMAN (265-390): 1.24e-10: 68.6: 28.57