Protein: AT2B3
Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3)

Gene: AT2B3, ATP2B3
Organism: Homo sapiens
Interactions: 86
UniProt ID: Q16720

Gene Ontology (top 5):
GO:0005388 - P-type calcium transporter activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0015085 - calcium ion transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1032587

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

15

High-throughput

0.811

High

627341

AT2B1
Plasma membrane calcium-transporting ATPase 1

2

14

High-throughput

0.789

High

1153389

CD226
CD226 antigen

1

9

High-throughput

0.691

High

158569

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

3

3

High-throughput

0.667

High

163002

H17B6
17-beta-hydroxysteroid dehydrogenase type 6

3

11

High-throughput

0.667

High

689827

CD27
CD27 antigen

3

9

High-throughput

0.667

High

705959

CD1B
T-cell surface glycoprotein CD1b

3

5

High-throughput

0.667

High

720669

AGTR1
Type-1 angiotensin II receptor

3

20

High-throughput

0.667

High

845398

PF2R
Prostaglandin F2-alpha receptor

3

18

High-throughput

0.667

High

967308

TSN5
Tetraspanin-5

3

13

High-throughput

0.667

High

1162286

DGUOK
Deoxyguanosine kinase, mitochondrial

3

1

High-throughput

0.667

High

1162295

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

3

20

High-throughput

0.667

High

1162301

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

3

3

High-throughput

0.667

High

930315

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

3

0

High-throughput

0.638

High

635153

CP2B6
Cytochrome P450 2B6

2

3

High-throughput

0.628

High

668996

FPR2
N-formyl peptide receptor 2

2

20

High-throughput

0.628

High

1159064

C3AR
C3a anaphylatoxin chemotactic receptor

2

20

High-throughput

0.628

High

1162297

GALT6
Polypeptide N-acetylgalactosaminyltransferase 6

2

1

High-throughput

0.628

High

1162299

LIRB4
Leukocyte immunoglobulin-like receptor subfamily B member 4

2

6

High-throughput

0.628

High

1162312

IPPK
Inositol-pentakisphosphate 2-kinase

2

1

High-throughput

0.628

High

692707

CALL3
Calmodulin-like protein 3

1

6

High-throughput

0.618

High

845661

MUC18
Cell surface glycoprotein MUC18

1

4

High-throughput

0.618

High

1101263

SLAF1
Signaling lymphocytic activation molecule

2

10

High-throughput

0.611

High

127342

LEG8
Galectin-8

3

11

High-throughput

0.609

High

834261

PLPL4
Patatin-like phospholipase domain-containing protein 4

3

1

High-throughput

0.609

High

251216

RNBP6
Ran-binding protein 6

2

1

High-throughput

0.574

High

702780

5HT2C
5-hydroxytryptamine receptor 2C

1

10

High-throughput

0.541

High

219441

S26A4
Pendrin

1

2

High-throughput

0.536

High

221454

OX2R
Orexin receptor type 2

1

9

High-throughput

0.536

High

378626

IL2RA
Interleukin-2 receptor subunit alpha

1

2

High-throughput

0.536

High

619824

VCAM1
Vascular cell adhesion protein 1

1

2

High-throughput

0.536

High

638197

S1PR1
Sphingosine 1-phosphate receptor 1

1

20

High-throughput

0.536

High

640388

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

20

High-throughput

0.536

High

719784

V2R
Vasopressin V2 receptor

1

16

High-throughput

0.536

High

774384

BASI
Basigin

1

11

High-throughput

0.536

High

832403

OPRX
Nociceptin receptor

1

20

High-throughput

0.536

High

833822

P2RY2
P2Y purinoceptor 2

1

20

High-throughput

0.536

High

834976

S19A1
Reduced folate transporter

1

3

High-throughput

0.536

High

867963

GLR
Glucagon receptor

1

2

High-throughput

0.536

High

906889

GPM6A
Neuronal membrane glycoprotein M6-a

1

1

High-throughput

0.536

High

956879

CXCR4
C-X-C chemokine receptor type 4

1

20

High-throughput

0.536

High

1162298

O13J1
Olfactory receptor 13J1

1

1

High-throughput

0.536

High

1162306

OPALI
Opalin

1

4

High-throughput

0.536

High

1162307

TR13C
Tumor necrosis factor receptor superfamily member 13C

1

1

High-throughput

0.536

High

1162311

ADAM7
Disintegrin and metalloproteinase domain-containing protein 7

1

4

High-throughput

0.536

High

1162314

ENTP7
Ectonucleoside triphosphate diphosphohydrolase 7

1

7

High-throughput

0.536

High

1162316

CLC4A
C-type lectin domain family 4 member A

1

3

High-throughput

0.536

High

1162317

NPTN
Neuroplastin

1

11

High-throughput

0.536

High

1162293

LRC55
Leucine-rich repeat-containing protein 55

1

0

High-throughput

0.513

High

1162310

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

253843

TPST2
Protein-tyrosine sulfotransferase 2

1

4

High-throughput

0.489

High

1022393

IDD
Integral membrane protein DGCR2/IDD

1

2

High-throughput

0.489

High

1162287

LEG9B
Galectin-9B

1

11

High-throughput

0.489

High

1162290

NIPA3
Magnesium transporter NIPA3

1

3

High-throughput

0.489

High

1162291

FOXR1
Forkhead box protein R1

1

2

High-throughput

0.489

High

1162296

CQ078
Uncharacterized protein C17orf78

1

4

High-throughput

0.489

High

1162300

F174A
Membrane protein FAM174A

1

4

High-throughput

0.489

High

1162308

IFT27
Intraflagellar transport protein 27 homolog

1

7

High-throughput

0.489

High

1162315

CC018
Uncharacterized protein C3orf18

1

2

High-throughput

0.489

High

241820

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

855452

ATRX
Transcriptional regulator ATRX

1

1

High-throughput

0.479

High

1035655

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.479

High

1162289

RNF43
E3 ubiquitin-protein ligase RNF43

1

5

High-throughput

0.479

High

1162309

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

10

High-throughput

0.479

High

419010

H2A1B
Histone H2A type 1-B/E

1

2

High-throughput

0.470

High

1162285

H2B2E
Histone H2B type 2-E

1

3

High-throughput

0.470

High

1162302

H2B1H
Histone H2B type 1-H

1

3

High-throughput

0.470

High

466033

ANXA6
Annexin A6

1

0

High-throughput

0.458

High

1162288

AGK
Acylglycerol kinase, mitochondrial

1

0

Small-scale

0.458

High

255047

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.445

High

538756

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

8

High-throughput

0.445

High

934682

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.445

High

971576

1433E
14-3-3 protein epsilon

1

6

Small-scale

0.445

High

1119151

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

6

High-throughput

0.445

High

1162292

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

8

High-throughput

0.445

High

106018

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

404090

GCR
Glucocorticoid receptor

1

9

High-throughput

0.437

High

1106922

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.437

High

1149894

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.437

High

1162294

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1162303

FAF2
FAS-associated factor 2

1

6

High-throughput

0.437

High

653342

HEMH
Ferrochelatase, mitochondrial

1

3

High-throughput

0.407

High

1007377

S35A2
UDP-galactose translocator

1

8

High-throughput

0.407

High

1162304

MFSD3
Major facilitator superfamily domain-containing protein 3

1

2

High-throughput

0.407

High

1162313

S35C2
Solute carrier family 35 member C2

1

1

High-throughput

0.407

High

1162305

TXD15
Thioredoxin domain-containing protein 15

3

0

High-throughput

0.347

High


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Last updated: 11Aug2025