Protein: AT2B2
Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)

Gene: AT2B2, ATP2B2
Organism: Homo sapiens
Interactions: 192
UniProt ID: Q01814

Gene Ontology (top 5):
GO:0005388 - P-type calcium transporter activity
GO:0005509 - calcium ion binding
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1032648

CAB45
45 kDa calcium-binding protein

3

7

High-throughput

0.861

High

661258

AT2B4
Plasma membrane calcium-transporting ATPase 4

2

15

High-throughput

0.811

High

821710

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

1

High-throughput

0.811

High

1032587

AT2B3
Plasma membrane calcium-transporting ATPase 3

2

15

High-throughput

0.811

High

1032677

VSIG4
V-set and immunoglobulin domain-containing protein 4

3

3

High-throughput

0.770

High

1029594

CD83
CD83 antigen

2

0

High-throughput

0.770

High

270637

ATP9A
Probable phospholipid-transporting ATPase IIA

1

8

High-throughput

0.691

High

1032601

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

5

High-throughput

0.691

High

127315

LEG8
Galectin-8

3

9

High-throughput

0.667

High

163001

H17B6
17-beta-hydroxysteroid dehydrogenase type 6

3

8

High-throughput

0.667

High

845396

PF2R
Prostaglandin F2-alpha receptor

3

18

High-throughput

0.667

High

1032684

SRPRB
Signal recognition particle receptor subunit beta

3

4

High-throughput

0.667

High

69612

CLM7
CMRF35-like molecule 7

1

0

High-throughput

0.656

High

1032599

BTNL9
Butyrophilin-like protein 9

1

0

High-throughput

0.656

High

914408

EFNB2
Ephrin-B2

3

0

High-throughput

0.638

High

1032602

DPH6
Diphthine--ammonia ligase

3

0

High-throughput

0.638

High

160700

TOR1A
Torsin-1A

2

2

High-throughput

0.628

High

190601

MRP4
ATP-binding cassette sub-family C member 4

2

3

High-throughput

0.628

High

270448

FZD7
Frizzled-7

2

4

High-throughput

0.628

High

296913

DGAT1
Diacylglycerol O-acyltransferase 1

2

1

High-throughput

0.628

High

320445

TM63A
Mechanosensitive cation channel TMEM63A

2

3

High-throughput

0.628

High

336537

PIGN
GPI ethanolamine phosphate transferase 1

2

1

High-throughput

0.628

High

419987

B3A2
Anion exchange protein 2

2

2

High-throughput

0.628

High

584518

VAV
Proto-oncogene vav

2

1

High-throughput

0.628

High

635152

CP2B6
Cytochrome P450 2B6

2

3

High-throughput

0.628

High

652184

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

2

11

High-throughput

0.628

High

665308

EDNRB
Endothelin receptor type B

2

20

High-throughput

0.628

High

668989

FPR2
N-formyl peptide receptor 2

2

20

High-throughput

0.628

High

699546

IL1R2
Interleukin-1 receptor type 2

2

1

High-throughput

0.628

High

702760

5HT2C
5-hydroxytryptamine receptor 2C

2

10

High-throughput

0.628

High

755340

ABCD1
ATP-binding cassette sub-family D member 1

2

6

High-throughput

0.628

High

845507

PI2R
Prostacyclin receptor

2

12

High-throughput

0.628

High

855315

5HT3A
5-hydroxytryptamine receptor 3A

2

2

High-throughput

0.628

High

903882

BAP31
B-cell receptor-associated protein 31

2

2

High-throughput

0.628

High

1032574

VAC14
Protein VAC14 homolog

2

2

High-throughput

0.628

High

1032591

TM63B
Mechanosensitive cation channel TMEM63B

2

3

High-throughput

0.628

High

1032592

MRP7
ATP-binding cassette sub-family C member 10

2

4

High-throughput

0.628

High

1032604

ATG9A
Autophagy-related protein 9A

2

2

High-throughput

0.628

High

1032605

S22AG
Solute carrier family 22 member 16

2

8

High-throughput

0.628

High

1032607

CHSS1
Chondroitin sulfate synthase 1

2

3

High-throughput

0.628

High

1032617

S15A4
Solute carrier family 15 member 4

2

7

High-throughput

0.628

High

1032621

UXS1
UDP-glucuronic acid decarboxylase 1

2

1

High-throughput

0.628

High

1032623

GALT6
Polypeptide N-acetylgalactosaminyltransferase 6

2

1

High-throughput

0.628

High

1032626

LIRB4
Leukocyte immunoglobulin-like receptor subfamily B member 4

2

5

High-throughput

0.628

High

1032642

BTBD9
BTB/POZ domain-containing protein 9

2

1

High-throughput

0.628

High

1032644

LPAR4
Lysophosphatidic acid receptor 4

2

20

High-throughput

0.628

High

1032664

ABCB9
ABC-type oligopeptide transporter ABCB9

2

4

High-throughput

0.628

High

1032665

ENTP7
Ectonucleoside triphosphate diphosphohydrolase 7

2

4

High-throughput

0.628

High

1032675

FZD10
Frizzled-10

2

4

High-throughput

0.628

High

1032679

RXLT1
Ribitol-5-phosphate xylosyltransferase 1

2

1

High-throughput

0.628

High

1032681

PCDGD
Protocadherin gamma-B1

2

2

High-throughput

0.628

High

627317

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

15

High-throughput

0.618

High

1032578

SLAF1
Signaling lymphocytic activation molecule

2

7

High-throughput

0.611

High

1032647

DHRS9
Dehydrogenase/reductase SDR family member 9

2

8

High-throughput

0.611

High

423763

APOD
Apolipoprotein D

2

0

High-throughput

0.602

High

501813

CO4A
Complement C4-A

2

0

High-throughput

0.602

High

533643

CLUS
Clusterin

2

0

High-throughput

0.602

High

671776

ZA2G
Zinc-alpha-2-glycoprotein

2

0

High-throughput

0.602

High

1032575

SIA4A
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1

2

0

High-throughput

0.602

High

1032582

ERG1
Squalene monooxygenase

2

0

High-throughput

0.602

High

1032594

STEA3
Metalloreductase STEAP3

2

0

High-throughput

0.602

High

1032603

ERMP1
Endoplasmic reticulum metallopeptidase 1

2

0

High-throughput

0.602

High

1032614

GHDC
GH3 domain-containing protein

2

0

High-throughput

0.602

High

1032619

GOLM1
Golgi membrane protein 1

2

0

High-throughput

0.602

High

1032622

LEMD2
LEM domain-containing protein 2

2

0

High-throughput

0.602

High

1032636

MUCL1
Mucin-like protein 1

2

0

High-throughput

0.602

High

1032663

GPAT1
Glycerol-3-phosphate acyltransferase 1, mitochondrial

2

0

High-throughput

0.602

High

1032683

TNPO3
Transportin-3

2

0

High-throughput

0.602

High

273756

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

2

3

High-throughput

0.574

High

1032618

GP161
G-protein coupled receptor 161

2

15

High-throughput

0.574

High

1032627

GOGA5
Golgin subfamily A member 5

2

1

High-throughput

0.574

High

1032628

F174A
Membrane protein FAM174A

2

3

High-throughput

0.574

High

1032630

PIGO
GPI ethanolamine phosphate transferase 3, catalytic subunit

2

1

High-throughput

0.574

High

1032640

FACR2
Fatty acyl-CoA reductase 2

2

1

High-throughput

0.574

High

1032658

PCX3
Pecanex-like protein 3

2

5

High-throughput

0.574

High

1032680

DHRS7
Dehydrogenase/reductase SDR family member 7

2

2

High-throughput

0.574

High

786

A0A087WZU1
Phosphatidylinositol phosphatase PTPRQ

1

2

High-throughput

0.536

High

48605

ESYT2
Extended synaptotagmin-2

1

3

High-throughput

0.536

High

161131

ABCD4
Lysosomal cobalamin transporter ABCD4

1

5

High-throughput

0.536

High

182510

GP182
G-protein coupled receptor 182

1

20

High-throughput

0.536

High

221451

OX2R
Orexin receptor type 2

1

9

High-throughput

0.536

High

226319

SNG1
Synaptogyrin-1

1

1

High-throughput

0.536

High

351890

S1PR4
Sphingosine 1-phosphate receptor 4

1

20

High-throughput

0.536

High

378619

IL2RA
Interleukin-2 receptor subunit alpha

1

2

High-throughput

0.536

High

569450

DHB1
17-beta-hydroxysteroid dehydrogenase type 1

1

10

High-throughput

0.536

High

638182

S1PR1
Sphingosine 1-phosphate receptor 1

1

20

High-throughput

0.536

High

640380

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

20

High-throughput

0.536

High

701801

ABCD3
ATP-binding cassette sub-family D member 3

1

8

High-throughput

0.536

High

709263

AA2BR
Adenosine receptor A2b

1

13

High-throughput

0.536

High

711551

NK3R
Neuromedin-K receptor

1

15

High-throughput

0.536

High

719778

V2R
Vasopressin V2 receptor

1

17

High-throughput

0.536

High

774296

BASI
Basigin

1

7

High-throughput

0.536

High

832397

OPRX
Nociceptin receptor

1

20

High-throughput

0.536

High

880129

PTH2R
Parathyroid hormone 2 receptor

1

1

High-throughput

0.536

High

890112

EI2BB
Translation initiation factor eIF2B subunit beta

1

3

High-throughput

0.536

High

906873

GPM6A
Neuronal membrane glycoprotein M6-a

1

1

High-throughput

0.536

High

907010

CCR6
C-C chemokine receptor type 6

1

20

High-throughput

0.536

High

907703

CLCN3
H(+)/Cl(-) exchange transporter 3

1

1

High-throughput

0.536

High

956848

CXCR4
C-X-C chemokine receptor type 4

1

20

High-throughput

0.536

High

1032577

KLRD1
Natural killer cells antigen CD94

1

8

High-throughput

0.536

High

1032581

FZD2
Frizzled-2

1

4

High-throughput

0.536

High

1032597

LYPD5
Ly6/PLAUR domain-containing protein 5

1

1

High-throughput

0.536

High

1032606

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

20

High-throughput

0.536

High

1032612

MIRO2
Mitochondrial Rho GTPase 2

1

18

High-throughput

0.536

High

1032620

S38A9
Neutral amino acid transporter 9

1

1

High-throughput

0.536

High

1032625

TSN14
Tetraspanin-14

1

6

High-throughput

0.536

High

1032629

TS1R2
Taste receptor type 1 member 2

1

1

High-throughput

0.536

High

1032638

S47A1
Multidrug and toxin extrusion protein 1

1

1

High-throughput

0.536

High

1032641

OPALI
Opalin

1

3

High-throughput

0.536

High

1032645

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

8

High-throughput

0.536

High

1032646

CML1
Chemerin-like receptor 1

1

20

High-throughput

0.536

High

1032651

S26A6
Solute carrier family 26 member 6

1

1

High-throughput

0.536

High

1032654

ADAM7
Disintegrin and metalloproteinase domain-containing protein 7

1

4

High-throughput

0.536

High

1032655

TTYH1
Protein tweety homolog 1

1

3

High-throughput

0.536

High

1032662

RXFP1
Relaxin receptor 1

1

7

High-throughput

0.536

High

1032667

GP173
Probable G-protein coupled receptor 173

1

10

High-throughput

0.536

High

1032682

PCDG7
Protocadherin gamma-A7

1

2

High-throughput

0.536

High

1032685

GPR45
Probable G-protein coupled receptor 45

1

20

High-throughput

0.536

High

1032686

NPTN
Neuroplastin

1

7

High-throughput

0.536

High

1032687

S4A7
Sodium bicarbonate cotransporter 3

1

2

High-throughput

0.536

High

506591

GPHRB
Golgi pH regulator B

2

1

High-throughput

0.533

High

1032579

SNTA1
Alpha-1-syntrophin

1

15

Small-scale

0.527

High

1032643

ERBIN
Erbin

1

5

Small-scale

0.527

High

1032583

LAGE3
EKC/KEOPS complex subunit LAGE3

1

0

High-throughput

0.513

High

1032608

K2C73
Keratin, type II cytoskeletal 73

1

0

High-throughput

0.513

High

1032610

INLR1
Interferon lambda receptor 1

1

0

High-throughput

0.513

High

1032632

RPGF5
Rap guanine nucleotide exchange factor 5

1

0

High-throughput

0.513

High

1032639

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.513

High

1032652

GPR88
G protein-coupled receptor 88

1

0

High-throughput

0.513

High

1032576

DLG1
Disks large homolog 1

1

10

Small-scale

0.508

High

85357

GPHRA
Golgi pH regulator A

2

1

High-throughput

0.504

High

1032580

SCRIB
Protein scribble homolog

1

14

High-throughput

0.501

High

377251

CALC
Calcitonin [Cleaved into: Calcitonin

1

1

Small-scale

0.500

High

71203

HIDE1
Protein HIDE1

1

1

High-throughput

0.489

High

253830

TPST2
Protein-tyrosine sulfotransferase 2

1

3

High-throughput

0.489

High

1022380

IDD
Integral membrane protein DGCR2/IDD

1

3

High-throughput

0.489

High

1032589

CL12B
C-type lectin domain family 12 member B

1

5

High-throughput

0.489

High

1032596

NIPA3
Magnesium transporter NIPA3

1

3

High-throughput

0.489

High

1032598

LCLT1
Lysocardiolipin acyltransferase 1

1

1

High-throughput

0.489

High

1032616

CQ078
Uncharacterized protein C17orf78

1

3

High-throughput

0.489

High

1032624

B3GN7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7

1

1

High-throughput

0.489

High

1032635

SLAF9
SLAM family member 9

1

2

High-throughput

0.489

High

1032674

CC018
Uncharacterized protein C3orf18

1

2

High-throughput

0.489

High

241432

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

380280

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

1

High-throughput

0.479

High

380418

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

1

High-throughput

0.479

High

713083

NOS3
Nitric oxide synthase 3

1

5

Small-scale

0.479

High

789093

NUP62
Nuclear pore glycoprotein p62

1

1

High-throughput

0.479

High

1032586

DLG2
Disks large homolog 2

1

10

Small-scale

0.479

High

1032588

DGUOK
Deoxyguanosine kinase, mitochondrial

1

1

High-throughput

0.479

High

1032593

OTU1
Ubiquitin thioesterase OTU1

1

1

High-throughput

0.479

High

1032633

DLG3
Disks large homolog 3

1

10

Small-scale

0.479

High

1032650

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

7

High-throughput

0.479

High

1032672

TA2R7
Taste receptor type 2 member 7

1

1

High-throughput

0.479

High

1032631

PIBF1
Progesterone-induced-blocking factor 1

1

0

High-throughput

0.458

High

1032634

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.458

High

1032671

KTU
Protein kintoun

1

0

High-throughput

0.458

High

1032585

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

12

Small-scale

0.457

High

948792

CD81
CD81 antigen

1

6

High-throughput

0.445

High

960365

SMS
Somatostatin

1

1

Small-scale

0.445

High

971418

1433E
14-3-3 protein epsilon

1

5

Small-scale

0.445

High

1032678

ITM2B
Integral membrane protein 2B

1

7

High-throughput

0.445

High

105776

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

122610

UBXN8
UBX domain-containing protein 8

1

1

High-throughput

0.437

High

1032676

S45A2
Membrane-associated transporter protein

1

1

High-throughput

0.437

High

94489

D6RGY6
Solute carrier family 45 member 2

1

1

High-throughput

0.407

High

1032657

TRABD
TraB domain-containing protein

3

0

High-throughput

0.347

High

1032661

SACA1
Sperm acrosome membrane-associated protein 1

3

0

High-throughput

0.347

High

1032668

GINM1
Glycoprotein integral membrane protein 1

3

0

High-throughput

0.347

High

1032673

NUFP1
FMR1-interacting protein NUFIP1

3

0

High-throughput

0.347

High

136491

GOLI4
Golgi integral membrane protein 4

2

0

High-throughput

0.328

High

339259

MPC2
Mitochondrial pyruvate carrier 2

2

0

High-throughput

0.328

High

690703

AOFB
Amine oxidase [flavin-containing] B

2

0

High-throughput

0.328

High

1032584

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

2

0

High-throughput

0.328

High

1032590

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

2

0

High-throughput

0.328

High

1032600

CERS6
Ceramide synthase 6

2

0

High-throughput

0.328

High

1032609

IFNL1
Interferon lambda-1

2

0

High-throughput

0.328

High

1032611

GLBL2
Beta-galactosidase-1-like protein 2

2

0

High-throughput

0.328

High

1032613

NRM
Nurim

2

0

High-throughput

0.328

High

1032653

TM168
Transmembrane protein 168

2

0

High-throughput

0.328

High

1032660

SPRNG
SREBP regulating gene protein

2

0

High-throughput

0.328

High

1032666

OSTC
Oligosaccharyltransferase complex subunit OSTC

2

0

High-throughput

0.328

High

1032595

SCAR3
Scavenger receptor class A member 3

2

0

High-throughput

0.318

High

168085

TIM23
Mitochondrial import inner membrane translocase subunit Tim23

1

0

High-throughput

0.279

Low

895234

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

High-throughput

0.279

Low

1032615

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.279

Low

1032637

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.279

Low

1032649

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

1

0

High-throughput

0.279

Low

1032656

G3ST2
Galactose-3-O-sulfotransferase 2

1

0

High-throughput

0.279

Low

1032659

TM134
Transmembrane protein 134

1

0

High-throughput

0.279

Low

1032669

DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

1

0

High-throughput

0.279

Low

1032670

TM39A
Transmembrane protein 39A

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025