HitPredict

Interactor 1: S10A2 (P29034)
Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)
Gene: S100A2

Interactor 2: KS6A1 (Q15418)
Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)
Gene: RPS6KA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 98 Hs			1 735
+	Hs
		642947 S10A4_HUMAN (2-97): 2.05e-38: 125: 61.46		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		615217 S10A1_HUMAN (2-91): 3.92e-38: 124: 52.22		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		638962 S100P_HUMAN (4-92): 8.31e-36: 118: 42.70		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		380782 S100B_HUMAN (4-92): 8.65e-33: 111: 44.94		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		416623 S10A6_HUMAN (2-93): 1.75e-30: 104: 46.74		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		707403 S10A3_HUMAN (2-98): 3.78e-36: 119: 43.30		AKT3_HUMAN (358-719): 9.26e-123: 377: 21.87
+	Hs
		681685 S10A3_HUMAN (2-98): 3.78e-36: 119: 43.30		AKT1_HUMAN (411-724): 3.69e-122: 375: 25.92
+	Hs
		682050 CRNN_HUMAN (2-91): 3.38e-30: 113: 25.56		AKT1_HUMAN (411-724): 3.69e-122: 375: 25.92
+	Hs
		380732 S100B_HUMAN (4-92): 8.65e-33: 111: 44.94		KAPCA_HUMAN (414-712): 3.66e-114: 350: 29.71
+	Hs
		682028 S10AE_HUMAN (4-85): 1.72e-21: 82.6: 25.61		AKT1_HUMAN (411-724): 3.69e-122: 375: 25.92