HitPredict

Interactor 1: LTK (P29376)
Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)
Gene: LTK

Interactor 2: DUS6 (Q16828)
Dual specificity protein phosphatase 6 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PYST1) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3)
Gene: DUSP6

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	28065597
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 864 Hs			1 381
+	Hs
		1259421 ALK_HUMAN (4-851): 0: 701: 54.51		DUS19_HUMAN (210-345): 2.77e-53: 177: 37.50
+	Hs
		1070972 ERBB4_HUMAN (277-847): 5.2e-131: 425: 21.37		DUS6_HUMAN (1-381): 1.09e-148: 427: 100.00
+	Hs
		1071007 ERBB4_HUMAN (277-847): 5.2e-131: 425: 21.37		DUS16_HUMAN (23-376): 8.48e-96: 301: 31.27
+	Hs
		609642 FGFR3_HUMAN (100-834): 2.96e-137: 429: 20.99		DUS10_HUMAN (2-349): 4.7e-96: 296: 33.43
+	Hs
		1071034 ERBB4_HUMAN (277-847): 5.2e-131: 425: 21.37		DUS10_HUMAN (2-349): 4.7e-96: 296: 33.43
+	Hs
		169190 MUSK_HUMAN (21-787): 1.09e-167: 510: 20.78		STYX_HUMAN (187-375): 1.18e-58: 191: 26.80
+	Hs
		434278 RET_HUMAN (278-849): 5.71e-146: 461: 25.98		DUS26_HUMAN (204-349): 1.57e-53: 178: 30.67
+	Hs
		304915 EPHA1_HUMAN (25-817): 9.44e-137: 433: 19.11		DUS14_HUMAN (206-359): 7.93e-59: 191: 32.47
+	Hs
		304916 FGFR2_HUMAN (163-833): 6.48e-137: 429: 20.03		DUS14_HUMAN (206-359): 7.93e-59: 191: 32.47
+	Hs
		435706 IGF1R_HUMAN (298-854): 3.35e-128: 419: 27.39		SSH1_HUMAN (203-381): 1.83e-56: 201: 34.81
+	Hs
		1070989 ERBB4_HUMAN (277-847): 5.2e-131: 425: 21.37		STYX_HUMAN (187-375): 1.18e-58: 191: 26.80
+	Hs
		304961 ERBB4_HUMAN (277-847): 5.2e-131: 425: 21.37		DUS14_HUMAN (206-359): 7.93e-59: 191: 32.47
+	Hs
		1070986 ERBB4_HUMAN (277-847): 5.2e-131: 425: 21.37		DUS18_HUMAN (193-363): 6.86e-58: 188: 27.17
+	Hs
		304908 IGF1R_HUMAN (298-854): 3.35e-128: 419: 27.39		DUS14_HUMAN (206-359): 7.93e-59: 191: 32.47
+	Hs
		435704 IGF1R_HUMAN (298-854): 3.35e-128: 419: 27.39		STYX_HUMAN (187-375): 1.18e-58: 191: 26.80
+	Hs
		435698 IGF1R_HUMAN (298-854): 3.35e-128: 419: 27.39		DUS18_HUMAN (193-363): 6.86e-58: 188: 27.17
+	Hs
		1070988 ERBB4_HUMAN (277-847): 5.2e-131: 425: 21.37		DUS19_HUMAN (210-345): 2.77e-53: 177: 37.50
+	Hs
		1071012 ERBB4_HUMAN (277-847): 5.2e-131: 425: 21.37		DUS21_HUMAN (199-355): 5.14e-53: 176: 25.48
+	Hs
		435671 IGF1R_HUMAN (298-854): 3.35e-128: 419: 27.39		DUS29_HUMAN (201-347): 8.97e-54: 179: 28.11
+	Hs
		435703 IGF1R_HUMAN (298-854): 3.35e-128: 419: 27.39		DUS19_HUMAN (210-345): 2.77e-53: 177: 37.50