HitPredict

Interactor 1: IL12B (P29460)
Interleukin-12 subunit beta (IL-12B) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (IL-12 subunit p40) (NK cell stimulatory factor chain 2) (NKSF2)
Gene: IL12B

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	15286281, 24012417
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:2000330 - positive regulation of T-helper 17 cell lineage commitment
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 328 Hs			1 2414
+	Hs
		667351 IL12B_HUMAN (1-328): 1.1e-115: 339: 100.00		CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25
+	Hs
		560478 PRLR_HUMAN (120-323): 2.89e-45: 164: 15.09		CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25