Interactor 1: MCM2 (P29469)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2)
Gene: MCM2
Interactor 2: CDC45 (Q08032)
Cell division control protein 45
Gene: CDC45
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.990 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9554851, 17167415, 23499444, 10757793, 27751725, 25659432, 25870112, 28510759, 26305950, 37968396, 15755447, 17018296, 28869037, 25313033, 26338774, 28373564, 32804080, 31728581, 19819872, 19496828 and 2 others
more... |
| Identification Methods | coimmunoprecipitation, anti tag coimmunoprecipitation, affinity chromatography technology, pull down, biochemical, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CDC45~MCM_lid, CDC45~MCM_N, CDC45~MCM_OB |
| Common GO terms | GO:0000727 - double-strand break repair via break-induced replication GO:0003682 - chromatin binding GO:0003688 - DNA replication origin binding GO:0003697 - single-stranded DNA binding GO:0005634 - nucleus and 5 others more... |
| Homologous interactions | 15 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
