HitPredict

Interactor 1: MCM2 (P29469)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2)
Gene: MCM2

Interactor 2: H2AZ (Q12692)
Histone H2A.Z
Gene: HTZ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	Histone~MCM2_N
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 868 Sc			1 134
+	Sc
		392073 MCM2_YEAST (18-868): 0: 960: 100.00		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50
+	Sc
		392333 MCM2_YEAST (18-868): 0: 960: 100.00		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		832655 MCM2_HUMAN (16-865): 0: 933: 46.96		H2A1A_HUMAN (7-134): 6e-53: 164: 55.81
+	Hs
		832672 MCM2_HUMAN (16-865): 0: 933: 46.96		H2A1J_HUMAN (7-133): 2.47e-52: 163: 55.47
+	Hs
		832683 MCM2_HUMAN (16-865): 0: 933: 46.96		H2AJ_HUMAN (7-134): 1.86e-52: 163: 55.81
+	Hs
		832496 MCM2_HUMAN (16-865): 0: 933: 46.96		H2A2C_HUMAN (7-134): 6.76e-52: 162: 55.04
+	Hs
		832567 MCM2_HUMAN (16-865): 0: 933: 46.96		H2A2B_HUMAN (7-129): 3.24e-52: 162: 56.45
+	Hs
		832648 MCM2_HUMAN (16-865): 0: 933: 46.96		H2A1H_HUMAN (7-133): 5.62e-52: 162: 55.47
+	Hs
		832523 MCM2_HUMAN (16-865): 0: 933: 46.96		H2A2A_HUMAN (7-133): 1.23e-51: 161: 55.47
+	Hs
		832548 MCM2_HUMAN (16-865): 0: 933: 46.96		H2A3_HUMAN (7-133): 1.38e-51: 161: 57.03
+	Hs
		832623 MCM2_HUMAN (16-865): 0: 933: 46.96		H2A1C_HUMAN (7-133): 1.5e-51: 161: 57.03
+	Hs
		469967 MCM2_HUMAN (16-865): 0: 933: 46.96		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		832543 MCM2_HUMAN (16-865): 0: 933: 46.96		H2AV_HUMAN (10-134): 1.67e-40: 133: 67.72
+	Hs
		391599 MCM2_HUMAN (16-865): 0: 933: 46.96		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		708464 MCM4_HUMAN (19-851): 0: 768: 26.31		H2A2A_HUMAN (7-133): 1.23e-51: 161: 55.47
+	Hs
		708663 MCM5_HUMAN (206-863): 0: 718: 32.33		H2A2C_HUMAN (7-134): 6.76e-52: 162: 55.04
+	Hs
		708681 MCM5_HUMAN (206-863): 0: 718: 32.33		H2A2A_HUMAN (7-133): 1.23e-51: 161: 55.47
+	Hs
		391569 MCM4_HUMAN (19-851): 0: 768: 26.31		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		469956 MCM5_HUMAN (206-863): 0: 718: 32.33		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		391570 MCM5_HUMAN (206-863): 0: 718: 32.33		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83