HitPredict

Interactor 1: SPB3 (P29508)
Serpin B3 (Protein T4-A) (Squamous cell carcinoma antigen 1) (SCCA-1)
Gene: SERPINB3

Interactor 2: SPB4 (P48594)
Serpin B4 (Leupin) (Peptidase inhibitor 11) (PI-11) (Squamous cell carcinoma antigen 2) (SCCA-2)
Gene: SERPINB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 26186194, 28514442, 24981860, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Serpin~Serpin
Common GO terms GO:0002020 - protease binding
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 1 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 390
Hs

1 390
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024