HitPredict

Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: CDC5L (Q99459)
Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein)
Gene: CDC5L

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10827081
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006281 - DNA repair
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 298 Hs			1 802
+	At
		1020089 MPK4_ARATH (7-296): 6.32e-132: 380: 38.05		CDC5L_ARATH (3-800): 3.93e-180: 540: 45.03
+	At
		1020088 MPK3_ARATH (9-296): 3.9e-130: 376: 34.92		CDC5L_ARATH (3-800): 3.93e-180: 540: 45.03
+	At
		663897 CDKA1_ARATH (1-289): 3.08e-144: 408: 68.62		MB3R4_ARATH (4-709): 6.8e-84: 289: 14.57
+	Hs
		519461 CDK2_HUMAN (1-298): 3.17e-166: 464: 100.00		MYBB_HUMAN (4-527): 1.92e-47: 182: 16.51
+	At
		1183755 MPK4_ARATH (7-296): 6.32e-132: 380: 38.05		Q9M118_ARATH (3-328): 9.8e-75: 248: 14.16
+	At
		1183682 MPK4_ARATH (7-296): 6.32e-132: 380: 38.05		MYB39_ARATH (4-349): 2.02e-72: 243: 17.32
+	At
		1175793 MPK3_ARATH (9-296): 3.9e-130: 376: 34.92		MYB96_ARATH (2-329): 8.82e-69: 233: 16.96
+	At
		1183751 MPK4_ARATH (7-296): 6.32e-132: 380: 38.05		MYB41_ARATH (3-280): 1.32e-68: 229: 16.08
+	At
		1183766 MPK4_ARATH (7-296): 6.32e-132: 380: 38.05		MYB92_ARATH (5-326): 8.36e-68: 229: 16.82
+	At
		101170 MPK4_ARATH (7-296): 6.32e-132: 380: 38.05		MYB88_ARATH (11-209): 1.83e-61: 217: 24.52
+	At
		1183774 MPK4_ARATH (7-296): 6.32e-132: 380: 38.05		Q9SRB0_ARATH (4-185): 7.69e-63: 217: 19.68
+	At
		1183542 MPK3_ARATH (9-296): 3.9e-130: 376: 34.92		MB3R5_ARATH (4-276): 4.05e-62: 220: 24.36
+	At
		101169 MPK3_ARATH (9-296): 3.9e-130: 376: 34.92		MYB88_ARATH (11-209): 1.83e-61: 217: 24.52
+	At
		101537 MPK3_ARATH (9-296): 3.9e-130: 376: 34.92		F4J1R5_ARATH (4-175): 5.32e-63: 215: 26.52
+	At
		1183673 MPK4_ARATH (7-296): 6.32e-132: 380: 38.05		MYB56_ARATH (4-128): 6.63e-52: 185: 28.57
+	At
		1183543 MPK3_ARATH (9-296): 3.9e-130: 376: 34.92		MYB56_ARATH (4-128): 6.63e-52: 185: 28.57
+	At
		1183768 MPK4_ARATH (7-296): 6.32e-132: 380: 38.05		WER_ARATH (6-150): 3.85e-51: 179: 28.29
+	At
		663881 CDKA1_ARATH (1-289): 3.08e-144: 408: 68.62		MB3R3_ARATH (9-109): 1.02e-09: 63.9: 36.28
+	At
		1169101 MPK4_ARATH (7-296): 6.32e-132: 380: 38.05		MY115_ARATH (5-86): 2.24e-12: 71.2: 39.02
+	At
		1169100 MPK3_ARATH (9-296): 3.9e-130: 376: 34.92		MY115_ARATH (5-86): 2.24e-12: 71.2: 39.02