Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2
Interactor 2: CDT1 (Q9H211)
DNA replication factor Cdt1 (Double parked homolog) (DUP)
Gene: CDT1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.91 | 0.60 | 0.739 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26496610, 31160578, 15004027, 14993212, 15855168, 23455922 |
| Identification Methods | affinity chromatography technology, pull down, enzymatic study, anti tag coimmunoprecipitation, coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045740 - positive regulation of DNA replication GO:0051301 - cell division |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
