Protein: CDK2
Cyclin-dependent kinase 2 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 cognate)

Gene: CDK2
Organism: Drosophila melanogaster
Interactions: 95
UniProt ID: P23573

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

660429

CCNE
G1/S-specific cyclin-E

7

20

Small-scale

0.950

High

660436

Q24159
Cyclin J

5

20

Small-scale

0.891

High

660459

Q961D1
Cyclin-K

3

20

High-throughput

0.839

High

660426

ERKA
Mitogen-activated protein kinase ERK-A

2

13

High-throughput

0.775

High

660456

CYCG
Cyclin G

2

20

Small-scale

0.775

High

660468

Q9VHN1
Cyclin-dependent kinases regulatory subunit

2

20

Small-scale

0.775

High

660442

Q7JNL9
Dacapo

2

2

Small-scale

0.757

High

575837

CCNA
G2/mitotic-specific cyclin-A

2

20

Small-scale

0.704

High

660430

P91654
Cdi4

2

2

Small-scale

0.674

High

567133

KPC3
Protein kinase C

1

7

High-throughput

0.656

High

620686

SXL
Protein sex-lethal

1

7

High-throughput

0.656

High

660422

CCNC
Cyclin-C

1

20

High-throughput

0.656

High

660444

GLIS2
Zinc finger protein GLIS2 homolog

1

3

High-throughput

0.656

High

660446

Q7K306
cyclin-dependent kinase

1

14

High-throughput

0.656

High

660485

Q9VZP3
Cyclin J, isoform A

1

20

High-throughput

0.656

High

660445

Q7K1V0
LD39136p

1

0

High-throughput

0.622

High

303989

O76513
Cyclin-H

1

20

High-throughput

0.621

High

195959

O17144
Cyclin-H

1

20

High-throughput

0.590

High

467101

CSK2A
Casein kinase II subunit alpha

1

19

High-throughput

0.590

High

660434

CKS1
Cyclin-dependent kinases regulatory subunit

1

20

Small-scale

0.590

High

660435

Q24158
Cyclin D

1

20

Small-scale

0.590

High

660452

HIPPO
Serine/threonine-protein kinase hippo

1

13

High-throughput

0.590

High

660454

PUF68
Poly(U)-binding-splicing factor hfp

1

7

High-throughput

0.590

High

660484

Q9VXM1
LD22957p

1

20

High-throughput

0.590

High

660486

Q9W0M9
GEO12020p1

1

9

High-throughput

0.590

High

660469

Q9VJ42
Uncharacterized protein, isoform A

2

5

High-throughput

0.565

High

467155

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.560

High

660447

Q7K4M9
LD31969p

1

0

High-throughput

0.560

High

660453

Q8T3L3
SD01232p

1

0

High-throughput

0.560

High

55513

A1Z9G1
FI19824p1

1

8

High-throughput

0.555

High

660427

RALA
Ras-related protein Ral-a

1

8

High-throughput

0.528

High

660431

P91668
Cyclin-dependent kinase inhibitor Dacapo

1

2

High-throughput

0.528

High

660448

Q7YZ95
S-phase kinase-associated protein 2

2

6

Small-scale

0.521

High

51798

GUS
Protein gustavus

1

8

High-throughput

0.508

High

84286

DIMM
Protein dimmed

1

1

High-throughput

0.508

High

458214

DFD
Homeotic protein deformed

1

10

High-throughput

0.508

High

559021

PP12
Serine/threonine-protein phosphatase alpha-2 isoform

1

13

High-throughput

0.508

High

660425

ECR
Ecdysone receptor

1

10

High-throughput

0.508

High

660439

RAD51
DNA repair protein Rad51 homolog

1

2

High-throughput

0.508

High

660457

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.508

High

660463

Q9VB23
Serine/threonine protein phosphatase 2A regulatory subunit

1

3

High-throughput

0.508

High

660473

Q9VL21
LD11652p

1

3

High-throughput

0.508

High

660474

Q9VL27
Alpha-galactosidase

1

1

High-throughput

0.508

High

660481

Q9VTX7
Eyegone, isoform A

1

9

High-throughput

0.508

High

660491

MED15
Mediator of RNA polymerase II transcription subunit 15

1

4

High-throughput

0.508

High

195731

ORC1
Origin recognition complex subunit 1

1

13

Small-scale

0.501

High

660437

ORC2
Origin recognition complex subunit 2

1

6

Small-scale

0.501

High

660455

Q8T965
Prefoldin subunit 3

1

0

High-throughput

0.486

High

660465

Q9VED4
Bard

1

0

High-throughput

0.486

High

660479

FRY
Protein furry

1

0

High-throughput

0.486

High

84598

B7YZX6
Uncharacterized protein, isoform B

1

5

High-throughput

0.481

High

117651

L0MPR7
Twin of eyeless, isoform C

1

9

High-throughput

0.481

High

660487

Q9W1H7
Putative homeodomain protein

1

4

High-throughput

0.481

High

660443

Q7JVY2
Double parked, isoform A

1

4

Small-scale

0.479

High

234923

PGAM5
Serine/threonine-protein phosphatase Pgam5, mitochondrial

1

2

High-throughput

0.464

High

660458

HRS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

2

High-throughput

0.464

High

660464

Q9VC60
BUD13 homolog

1

4

High-throughput

0.464

High

660475

POLZ2
DNA polymerase zeta subunit 2

1

1

High-throughput

0.464

High

660433

STAT
Signal transducer and transcription activator

1

0

Small-scale

0.458

High

198134

GBLP
Small ribosomal subunit protein RACK1

1

14

High-throughput

0.457

High

303720

O76136
Homeodomain protein

1

8

High-throughput

0.457

High

303948

RAD54
DNA repair and recombination protein RAD54-like

1

2

High-throughput

0.457

High

654195

DDX6
ATP-dependent RNA helicase me31b

1

10

High-throughput

0.457

High

660423

XPA
DNA repair protein complementing XP-A cells homolog

1

1

High-throughput

0.457

High

660424

VATB
V-type proton ATPase subunit B

1

7

High-throughput

0.457

High

660428

PRS4
26S proteasome regulatory subunit 4

1

5

High-throughput

0.457

High

660440

NLP
Nucleoplasmin-like protein

1

4

High-throughput

0.457

High

660450

UBP2
Ubiquitin carboxyl-terminal hydrolase Usp2

1

5

High-throughput

0.457

High

660461

Q9V490
GH14454p

1

10

High-throughput

0.457

High

660466

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.457

High

660470

Q9VJZ6
LD40224p

1

7

High-throughput

0.457

High

660477

Q9VRS0
Importin subunit alpha

1

5

High-throughput

0.457

High

660488

Q9W1L8
GH11818p

1

1

High-throughput

0.457

High

660489

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.457

High

95619

E3CTS2
MIP27658p

1

3

High-throughput

0.439

High

121530

M9PFH3
Uncharacterized protein, isoform D

1

1

High-throughput

0.439

High

660492

X2JLM6
Ubiquitin carboxyl-terminal hydrolase

1

5

High-throughput

0.439

High

660441

Y1411
WD repeat-containing protein CG11141

1

0

High-throughput

0.438

High

660460

FADD
Fas-associated death domain protein

1

0

High-throughput

0.438

High

660432

Q24036
Failed axon connections protein

1

1

High-throughput

0.417

High

660449

Q8IGS9
U6 snRNA-associated Sm-like protein LSm4

1

4

High-throughput

0.417

High

660451

Q8SYU4
RE33778p

1

3

High-throughput

0.417

High

660462

Q9VAJ2
Mitotic checkpoint protein BUB3

1

13

High-throughput

0.417

High

660472

Q9VKW8
U6 snRNA-associated Sm-like protein LSm4

1

4

High-throughput

0.417

High

660476

Q9VRP2
Uncharacterized protein, isoform A

1

1

High-throughput

0.417

High

660480

ULA1
Nedd8-activating enzyme E1 regulatory subunit

1

2

High-throughput

0.417

High

660482

Q9VU23
Uncharacterized protein, isoform E

1

1

High-throughput

0.417

High

660490

Q9Y138
BcDNA.GH06193

1

8

High-throughput

0.417

High

660438

RBF
Retinoblastoma family protein

1

11

High-throughput

0.381

High

561050

VTU2
Vitelline membrane protein Vm26Ab

1

0

High-throughput

0.265

Low

660467

Q9VH02
LD30822p

1

0

High-throughput

0.265

Low

660471

Q9VKF2
RE59904p

1

0

High-throughput

0.265

Low

660483

Q9VWT7
GEO07745p1

1

0

High-throughput

0.265

Low

235023

O46100
Solute carrier family 12 member 8

1

0

High-throughput

0.238

Low

660478

Q9VSF5
GH02649p

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025