HitPredict

Interactor 1: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	36931259, 38334954, 15161933
Identification Methods	proximity labelling technology, cross-linking study, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2843 Hs			1 245
+	Hs
		668549 APC_HUMAN (1-2843): 0: 1286: 100.00		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Hs
		668551 APC_HUMAN (1-2843): 0: 1286: 100.00		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		668512 APC_HUMAN (1-2843): 0: 1286: 100.00		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		668513 APC_HUMAN (1-2843): 0: 1286: 100.00		1433S_HUMAN (1-236): 9.9e-108: 312: 71.85
+	Hs
		668564 APC_HUMAN (1-2843): 0: 1286: 100.00		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		668547 APC_HUMAN (1-2843): 0: 1286: 100.00		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33
+	Hs
		274129 ANR17_HUMAN (1869-2843): 7.16e-68: 258: 14.65		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Hs
		274099 ANR17_HUMAN (1869-2843): 7.16e-68: 258: 14.65		1433T_HUMAN (1-245): 9.51e-142: 398: 100.00
+	Hs
		274131 ANR17_HUMAN (1869-2843): 7.16e-68: 258: 14.65		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		274105 ANR17_HUMAN (1869-2843): 7.16e-68: 258: 14.65		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		274106 ANR17_HUMAN (1869-2843): 7.16e-68: 258: 14.65		1433S_HUMAN (1-236): 9.9e-108: 312: 71.85
+	Hs
		274138 ANR17_HUMAN (1869-2843): 7.16e-68: 258: 14.65		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		274127 ANR17_HUMAN (1869-2843): 7.16e-68: 258: 14.65		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33
+	Hs
		971417 ANK2_HUMAN (732-2368): 6.71e-37: 156: 10.07		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Hs
		690915 ANK2_HUMAN (732-2368): 6.71e-37: 156: 10.07		1433T_HUMAN (1-245): 9.51e-142: 398: 100.00
+	Hs
		990109 ANK2_HUMAN (732-2368): 6.71e-37: 156: 10.07		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		334286 TACC2_HUMAN (817-2843): 1.02e-30: 136: 7.20		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Hs
		691291 TITIN_HUMAN (731-2590): 1.4e-32: 142: 7.93		1433T_HUMAN (1-245): 9.51e-142: 398: 100.00
+	Hs
		990550 TITIN_HUMAN (731-2590): 1.4e-32: 142: 7.93		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		334287 TACC2_HUMAN (817-2843): 1.02e-30: 136: 7.20		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59