HitPredict

Interactor 1: BRD2 (P25440)
Bromodomain-containing protein 2 (O27.1.1)
Gene: BRD2

Interactor 2: H33 (P84243)
Histone H3.3
Gene: H3-3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36089195, 29044188
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 801 Hs			1 136
+	Hs
		674131 BRD2_HUMAN (1-773): 1.65e-170: 514: 100.00		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		674107 BRD2_HUMAN (1-773): 1.65e-170: 514: 100.00		CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76
+	Hs
		998336 BRD3_HUMAN (53-764): 8.33e-122: 384: 56.56		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		1016874 BRD3_HUMAN (53-764): 8.33e-122: 384: 56.56		H33_HUMAN (1-136): 1.13e-59: 182: 100.00
+	Hs
		883545 BRD3_HUMAN (53-764): 8.33e-122: 384: 56.56		CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76
+	Hs
		998251 EP300_HUMAN (31-183): 5.55e-39: 159: 30.72		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		1016806 EP300_HUMAN (31-183): 5.55e-39: 159: 30.72		H33_HUMAN (1-136): 1.13e-59: 182: 100.00
+	Hs
		1067400 EP300_HUMAN (31-183): 5.55e-39: 159: 30.72		H31T_HUMAN (1-136): 2.59e-59: 181: 93.38
+	Hs
		1067452 EP300_HUMAN (31-183): 5.55e-39: 159: 30.72		H32_HUMAN (1-136): 5.34e-59: 180: 97.06
+	Sc
		918517 RSC1_YEAST (75-483): 2.91e-40: 161: 16.55		H3_YEAST (1-136): 3.63e-54: 168: 90.44
+	Hs
		1162078 BRPF3_HUMAN (204-764): 1.44e-35: 147: 15.59		H31T_HUMAN (1-136): 2.59e-59: 181: 93.38
+	Sc
		963682 GCN5_YEAST (275-456): 3e-40: 155: 26.63		H3_YEAST (1-136): 3.63e-54: 168: 90.44
+	Dm
		381706 Q4V5A7_DROME (58-211): 2.31e-33: 139: 31.17		H3_DROME (1-136): 5.34e-59: 180: 97.06
+	At
		947414 GCN5_ARATH (351-449): 7.84e-33: 136: 37.62		H33_ARATH (1-136): 3.85e-60: 183: 95.59
+	Hs
		998633 KAT2B_HUMAN (293-452): 7.65e-32: 135: 25.00		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		1017078 KAT2B_HUMAN (293-452): 7.65e-32: 135: 25.00		H33_HUMAN (1-136): 1.13e-59: 182: 100.00
+	Hs
		1161979 KAT2B_HUMAN (293-452): 7.65e-32: 135: 25.00		H31T_HUMAN (1-136): 2.59e-59: 181: 93.38
+	Hs
		1258900 KAT2B_HUMAN (293-452): 7.65e-32: 135: 25.00		H32_HUMAN (1-136): 5.34e-59: 180: 97.06
+	Sc
		963738 RSC2_YEAST (332-734): 3.52e-31: 133: 18.32		H3_YEAST (1-136): 3.63e-54: 168: 90.44
+	Sc
		779353 RSC2_YEAST (332-734): 3.52e-31: 133: 18.32		CENPA_YEAST (41-134): 2.79e-31: 112: 67.01