Protein: RSC2
Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2)

Gene: RSC2
Organism: Saccharomyces cerevisiae S288C
Interactions: 114
UniProt ID: Q06488

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0003682 - chromatin binding
GO:0006276 - plasmid maintenance
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0006337 - nucleosome disassembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743143

STH1
Nuclear protein STH1/NPS1

23

19

Small-scale

0.989

High

1035336

RSC4
Chromatin structure-remodeling complex subunit RSC4

16

19

Small-scale

0.981

High

1055384

RSC58
Chromatin structure-remodeling complex protein RSC58

11

4

Small-scale

0.974

High

918528

RSC1
Chromatin structure-remodeling complex subunit RSC1

4

20

Small-scale

0.860

High

963738

H3
Histone H3

5

20

Small-scale

0.823

High

823046

ATAD2
ATPase histone chaperone YTA7

3

13

High-throughput

0.817

High

382365

H4
Histone H4

4

20

Small-scale

0.792

High

1050597

ARP9
Actin-like protein ARP9

14

20

Small-scale

0.759

High

850584

RSC8
Chromatin structure-remodeling complex protein RSC8

14

20

Small-scale

0.759

High

1055383

RSC3
Chromatin structure-remodeling complex protein RSC3

13

9

Small-scale

0.759

High

678348

RSC6
Chromatin structure-remodeling complex protein RSC6

13

20

Small-scale

0.758

High

1055392

ARP7
Actin-related protein 7

13

20

Small-scale

0.758

High

1041005

RSC9
Chromatin structure-remodeling complex subunit RSC9

13

4

Small-scale

0.757

High

1054036

SFH1
Chromatin structure-remodeling complex subunit SFH1

12

18

Small-scale

0.755

High

745619

RSC7
Chromatin structure-remodeling complex subunit RSC7

11

5

Small-scale

0.755

High

381277

H2B1
Histone H2B.1

3

20

High-throughput

0.751

High

919694

RT102
Regulator of Ty1 transposition protein 102

8

5

Small-scale

0.749

High

804007

RSC30
Chromatin structure-remodeling complex protein RSC30

7

9

Small-scale

0.741

High

419884

H2A2
Histone H2A.2

3

20

High-throughput

0.731

High

1055397

HTL1
High temperature lethal protein 1

4

4

Small-scale

0.673

High

1055382

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

20

High-throughput

0.665

High

796039

LDB7
Chromatin structure-remodeling complex protein RSC14

3

4

Small-scale

0.640

High

794226

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

2

20

High-throughput

0.621

High

1042812

NHP10
Non-histone protein 10

2

20

High-throughput

0.621

High

419515

H2A1
Histone H2A.1

1

20

High-throughput

0.618

High

777124

BDF1
Bromodomain-containing factor 1

1

20

High-throughput

0.618

High

739784

SPT16
FACT complex subunit SPT16

2

11

High-throughput

0.594

High

1055390

RIO1
Serine/threonine-protein kinase RIO1

2

4

Small-scale

0.586

High

826860

DSN1
Kinetochore-associated protein DSN1

2

3

High-throughput

0.584

High

1044590

HMO1
High mobility group protein 1

2

20

Small-scale

0.584

High

1044766

SCC2
Sister chromatid cohesion protein 2

2

5

Small-scale

0.584

High

727335

HS104
Heat shock protein 104

1

7

High-throughput

0.578

High

736735

ASF1
Histone chaperone ASF1

1

10

High-throughput

0.575

High

1042379

GCN5
Histone acetyltransferase GCN5

1

20

High-throughput

0.575

High

1055396

H2AZ
Histone H2A.Z

1

20

High-throughput

0.575

High

638819

REB1
DNA-binding protein REB1

2

4

High-throughput

0.567

High

381643

H2B2
Histone H2B.2

1

20

High-throughput

0.553

High

779353

CENPA
Histone H3-like centromeric protein CSE4

1

20

High-throughput

0.553

High

745537

MRE11
Double-strand break repair protein MRE11

1

4

Small-scale

0.552

High

542991

CDC24
Cell division control protein 24

2

2

High-throughput

0.549

High

546394

SSB1
Ribosome-associated molecular chaperone SSB1

2

20

High-throughput

0.549

High

877589

RFX1
RFX-like DNA-binding protein RFX1

2

10

High-throughput

0.537

High

525251

HSP71
Heat shock protein SSA1

2

20

High-throughput

0.533

High

527762

HSP72
Heat shock protein SSA2

2

20

High-throughput

0.533

High

740016

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

2

9

Small-scale

0.533

High

818514

SCC4
MAU2 chromatid cohesion factor homolog

2

3

Small-scale

0.533

High

1055391

RAD59
DNA repair protein RAD59

1

1

Small-scale

0.527

High

764012

SPT10
Protein SPT10

2

5

High-throughput

0.521

High

752772

HSP78
Heat shock protein 78, mitochondrial

1

7

High-throughput

0.514

High

742470

HSP7F
Heat shock protein homolog SSE1

2

20

High-throughput

0.504

High

819879

SSB2
Ribosome-associated molecular chaperone SSB2

2

20

High-throughput

0.504

High

561537

TBP
TATA-box-binding protein

1

10

High-throughput

0.479

High

795231

NU170
Nucleoporin NUP170

1

3

High-throughput

0.479

High

1055389

SCC1
Sister chromatid cohesion protein 1

1

6

High-throughput

0.479

High

805705

YHS2
MIP18 family protein YHR122W

1

1

High-throughput

0.457

High

547829

NHP6A
Non-histone chromosomal protein 6A

1

20

High-throughput

0.445

High

645648

AFT1
Iron-regulated transcriptional activator AFT1

1

3

High-throughput

0.445

High

754250

MSN4
Zinc finger protein MSN4

1

20

High-throughput

0.445

High

858476

TAF1
Transcription initiation factor TFIID subunit 1

1

10

High-throughput

0.445

High

1044153

GIS1
Transcriptional activator/repressor GIS1

1

20

High-throughput

0.445

High

1051134

SWR1
Helicase SWR1

1

20

High-throughput

0.445

High

149967

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.437

High

383906

RS17A
Small ribosomal subunit protein eS17A

1

4

High-throughput

0.437

High

410350

RL25
Large ribosomal subunit protein uL23

1

7

High-throughput

0.437

High

435378

RS3
Small ribosomal subunit protein uS3

1

7

High-throughput

0.437

High

436184

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.437

High

442123

RS14A
Small ribosomal subunit protein uS11A

1

4

High-throughput

0.437

High

449012

TOP2
DNA topoisomerase 2

1

19

High-throughput

0.437

High

455276

RS19A
Small ribosomal subunit protein eS19A

1

6

High-throughput

0.437

High

503254

RS22A
Small ribosomal subunit protein uS8A

1

4

High-throughput

0.437

High

504429

RL31A
Large ribosomal subunit protein eL31A

1

5

High-throughput

0.437

High

513234

RS8A
Small ribosomal subunit protein eS8A

1

6

High-throughput

0.437

High

514848

RS18A
Small ribosomal subunit protein uS13A

1

4

High-throughput

0.437

High

674849

RS2
Small ribosomal subunit protein uS5

1

6

High-throughput

0.437

High

689677

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.437

High

708267

TF2B
Transcription initiation factor IIB

1

12

High-throughput

0.437

High

735178

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

5

High-throughput

0.437

High

745885

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

11

High-throughput

0.437

High

747592

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

748061

SMY2
Protein SMY2

1

5

High-throughput

0.437

High

751539

YKJ1
CRAL-TRIO domain-containing protein YKL091C

1

1

Small-scale

0.437

High

753598

RS3A1
Small ribosomal subunit protein eS1A

1

7

High-throughput

0.437

High

778546

RS27A
Small ribosomal subunit protein eS27A

1

3

High-throughput

0.437

High

792262

GBLP
Small ribosomal subunit protein RACK1

1

19

High-throughput

0.437

High

802400

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.437

High

825778

MAM33
Mitochondrial acidic protein MAM33

1

5

High-throughput

0.437

High

826405

MPH1
ATP-dependent DNA helicase MPH1

1

20

High-throughput

0.437

High

874541

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.437

High

921169

H1
Histone H1

1

1

Small-scale

0.437

High

925078

APJ1
J domain-containing protein APJ1

1

19

High-throughput

0.437

High

1033580

RS15
Small ribosomal subunit protein uS19

1

4

High-throughput

0.437

High

1046936

POB3
FACT complex subunit POB3

1

13

High-throughput

0.437

High

1055385

MED7
Mediator of RNA polymerase II transcription subunit 7

1

3

Small-scale

0.437

High

1055386

SGO1
Shugoshin

1

3

High-throughput

0.437

High

1055387

RS10A
Small ribosomal subunit protein eS10A

1

7

High-throughput

0.437

High

1055388

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

4

High-throughput

0.437

High

1055395

CMR1
DNA damage-binding protein CMR1

1

20

High-throughput

0.437

High

393378

HSP82
ATP-dependent molecular chaperone HSP82

1

13

High-throughput

0.407

High

448227

HAP2
Transcriptional activator HAP2

1

6

High-throughput

0.407

High

489004

SWI6
Regulatory protein SWI6

1

19

High-throughput

0.407

High

548802

MCM1
Pheromone receptor transcription factor

1

4

High-throughput

0.407

High

550083

RAP1
DNA-binding protein RAP1

1

4

High-throughput

0.407

High

671561

SWI4
Regulatory protein SWI4

1

18

High-throughput

0.407

High

752991

IXR1
Intrastrand cross-link recognition protein

1

20

High-throughput

0.407

High

781808

SET3
SET domain-containing protein 3

1

20

High-throughput

0.407

High

836910

MPG1
Mannose-1-phosphate guanyltransferase

1

4

High-throughput

0.407

High

844449

TCPH
T-complex protein 1 subunit eta

1

7

High-throughput

0.407

High

1040028

HOS3
Histone deacetylase HOS3

1

20

High-throughput

0.407

High

1046751

PFD5
Prefoldin subunit 5

1

1

High-throughput

0.407

High

1055394

CAF1A
Chromatin assembly factor 1 subunit A

1

11

High-throughput

0.407

High

1055393

PCL9
PHO85 cyclin-9

1

0

High-throughput

0.269

Low

780862

MUD2
Splicing factor MUD2

1

0

High-throughput

0.265

Low

776545

NU120
Nucleoporin NUP120

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025