HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: ARL4D (P49703)
ADP-ribosylation factor-like protein 4D (ADP-ribosylation factor-like protein 4L)
Gene: ARL4D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Hs			1 201
+	Hs
		574602 UFO_HUMAN (1-894): 0: 780: 100.00		ARF4_HUMAN (8-190): 2.95e-81: 240: 38.71
+	Hs
		674380 UFO_HUMAN (1-894): 0: 780: 100.00		ARF6_HUMAN (14-185): 1.62e-79: 236: 40.12
+	Hs
		912916 EPHA7_HUMAN (2-837): 0: 621: 19.50		ARF6_HUMAN (14-185): 1.62e-79: 236: 40.12
+	Hs
		665188 EPHA2_HUMAN (3-837): 0: 604: 19.66		ARL4C_HUMAN (12-200): 1.37e-83: 247: 58.73
+	Hs
		665207 EPHA2_HUMAN (3-837): 0: 604: 19.66		ARF5_HUMAN (8-190): 2.28e-82: 244: 39.79
+	Hs
		665572 EPHB2_HUMAN (2-837): 0: 605: 19.58		ARF6_HUMAN (14-185): 1.62e-79: 236: 40.12
+	Hs
		665196 EPHA2_HUMAN (3-837): 0: 604: 19.66		ARF6_HUMAN (14-185): 1.62e-79: 236: 40.12
+	Hs
		574601 EPHA8_HUMAN (2-824): 0: 590: 19.20		ARF4_HUMAN (8-190): 2.95e-81: 240: 38.71
+	Hs
		665173 EPHA2_HUMAN (3-837): 0: 604: 19.66		RAB5C_HUMAN (1-201): 4.14e-64: 198: 18.32
+	Hs
		665197 EPHA2_HUMAN (3-837): 0: 604: 19.66		RB11A_HUMAN (11-200): 8.5e-64: 198: 21.47
+	Hs
		592117 EPHA2_HUMAN (3-837): 0: 604: 19.66		RAB5A_HUMAN (1-201): 1.91e-63: 197: 18.81
+	Hs
		665466 EPHA8_HUMAN (2-824): 0: 590: 19.20		RB11A_HUMAN (11-200): 8.5e-64: 198: 21.47
+	Hs
		872520 EPHB4_HUMAN (2-836): 1.08e-180: 549: 20.49		ARF6_HUMAN (14-185): 1.62e-79: 236: 40.12
+	Hs
		574656 TIE2_HUMAN (16-809): 3.58e-164: 510: 23.90		ARF4_HUMAN (8-190): 2.95e-81: 240: 38.71
+	Hs
		411349 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		ARF6_HUMAN (14-185): 1.62e-79: 236: 40.12
+	Hs
		411339 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		RAB5C_HUMAN (1-201): 4.14e-64: 198: 18.32
+	Hs
		411350 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		RB11A_HUMAN (11-200): 8.5e-64: 198: 21.47
+	Rn
		69451 INSR_RAT (276-851): 1.26e-134: 437: 27.83		B0BNK1_RAT (1-201): 3.22e-64: 199: 18.32
+	Rn
		69428 INSR_RAT (276-851): 1.26e-134: 437: 27.83		B0BMW0_RAT (17-199): 1.01e-63: 197: 20.11
+	Hs
		411437 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		ARL14_HUMAN (17-196): 2.29e-46: 152: 42.22