HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0043066 - negative regulation of apoptotic process GO:0045087 - innate immune response
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 894 Hs			1 4128
+	Hs
		665578 EPHB2_HUMAN (2-837): 0: 605: 19.58		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		944208 MERTK_HUMAN (7-861): 0: 588: 40.53		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		600550 EPHA1_HUMAN (1-837): 0: 555: 20.58		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		944192 TIE2_HUMAN (16-809): 3.58e-164: 510: 23.90		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		445842 ROS1_HUMAN (284-804): 1.68e-56: 214: 31.27		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		944196 RON_HUMAN (518-810): 1.36e-56: 214: 40.47		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		713782 RYK_HUMAN (521-810): 4.45e-57: 209: 37.63		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		601494 FGFR2_HUMAN (27-239): 5.42e-33: 139: 14.46		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		609246 FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		944199 TYRO3_HUMAN (8-328): 1.16e-14: 80.5: 16.42		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		435610 IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		872435 EPHA5_HUMAN (2-812): 0: 622: 20.39		ATM_HUMAN (3218-4128): 1.84e-158: 557: 19.42
+	Hs
		445886 ROS1_HUMAN (284-804): 1.68e-56: 214: 31.27		TRRAP_HUMAN (2754-4128): 0: 828: 15.88
+	Hs
		600653 EPHA1_HUMAN (1-837): 0: 555: 20.58		SMG1_HUMAN (3179-4115): 6.6e-124: 444: 16.20