HitPredict

Interactor 1: AMRP (P30533)
Alpha-2-macroglobulin receptor-associated protein (Alpha-2-MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP)
Gene: LRPAP1

Interactor 2: LRP8 (Q14114)
Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2)
Gene: LRP8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.947

The method score is based on:

Property Details
Experiments 10231386, 28514442, 12899622, 16101684, 33961781, 20223215
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Alpha-2-MRAP_C~Ldl_recept_a, Alpha-2-MRAP_N~Ldl_recept_a
Common GO terms GO:0001540 - amyloid-beta binding
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0009986 - cell surface
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 357
Hs

1 963
+ Hs
+ Hs
+ Hs
+ Gg
+ Hs
+ Hs
+ Hs
+ Hs
+ Gg
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024