Protein: RFC5
Replication factor C subunit 5 (Replication factor C5) (Activator 1 40 kDa subunit)

Gene: RFC5
Organism: Saccharomyces cerevisiae S288C
Interactions: 78
UniProt ID: P38251

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0003677 - DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005663 - DNA replication factor C complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

796704

RFC2
Replication factor C subunit 2

9

17

Small-scale

0.968

High

796709

CTF18
Chromosome transmission fidelity protein 18

8

20

Small-scale

0.966

High

796693

RFC3
Replication factor C subunit 3

5

16

High-throughput

0.927

High

586451

PCNA
Proliferating cell nuclear antigen

5

15

Small-scale

0.924

High

796694

RFC1
Replication factor C subunit 1

4

20

High-throughput

0.896

High

796703

RFC4
Replication factor C subunit 4

3

18

High-throughput

0.855

High

796725

ELG1
Telomere length regulation protein ELG1

10

20

Small-scale

0.754

High

744192

RAD24
Checkpoint protein RAD24

8

20

Small-scale

0.749

High

793818

DPOA2
DNA polymerase alpha subunit B

2

2

High-throughput

0.621

High

796696

CTF8
Chromosome transmission fidelity protein 8

2

3

Small-scale

0.621

High

676831

DCC1
Sister chromatid cohesion protein DCC1

2

7

High-throughput

0.601

High

796712

H3
Histone H3

2

13

High-throughput

0.601

High

448959

TOP2
DNA topoisomerase 2

2

1

High-throughput

0.588

High

382056

H4
Histone H4

2

7

High-throughput

0.584

High

419714

H2A2
Histone H2A.2

2

7

High-throughput

0.584

High

796727

HSP42
Heat shock protein 42

2

2

High-throughput

0.537

High

721885

XPO1
Exportin-1

1

7

High-throughput

0.536

High

763064

RRP1
Ribosomal RNA-processing protein 1

1

2

High-throughput

0.515

High

796701

SNU13
13 kDa ribonucleoprotein-associated protein

1

1

High-throughput

0.515

High

796707

ECO1
N-acetyltransferase ECO1

1

3

Small-scale

0.515

High

794954

NU170
Nucleoporin NUP170

1

3

High-throughput

0.504

High

796698

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

796699

IFH1
Protein IFH1

1

0

High-throughput

0.493

High

649607

KCC2
Calcium/calmodulin-dependent protein kinase II

1

0

High-throughput

0.480

High

381085

H2B1
Histone H2B.1

1

14

High-throughput

0.479

High

381501

H2B2
Histone H2B.2

1

14

High-throughput

0.479

High

416811

DNLI1
DNA ligase 1

1

3

Small-scale

0.479

High

435045

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

579283

HSC82
ATP-dependent molecular chaperone HSC82

1

6

High-throughput

0.479

High

594342

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.479

High

706919

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

734948

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

3

High-throughput

0.479

High

736639

ASF1
Histone chaperone ASF1

1

3

Small-scale

0.479

High

745717

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

3

High-throughput

0.479

High

792008

GBLP
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.479

High

796705

ULP2
Ubiquitin-like-specific protease 2

1

3

High-throughput

0.479

High

796706

DSN1
Kinetochore-associated protein DSN1

1

3

High-throughput

0.479

High

796711

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

8

Small-scale

0.479

High

796715

RUVB1
RuvB-like protein 1

1

11

High-throughput

0.479

High

796721

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

2

High-throughput

0.479

High

796723

SGO1
Shugoshin

1

3

High-throughput

0.479

High

796726

SCC1
Sister chromatid cohesion protein 1

1

4

High-throughput

0.479

High

796728

RUVB2
RuvB-like protein 2

1

11

High-throughput

0.479

High

796719

EIS1
Eisosome protein 1

1

1

High-throughput

0.470

High

796718

IVY1
Protein IVY1

1

1

High-throughput

0.464

High

796697

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

796716

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

796717

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

523743

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

526522

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

544642

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

796702

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

149725

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.437

High

383667

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.437

High

410088

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.437

High

433603

RL26A
Large ribosomal subunit protein uL24A

1

6

High-throughput

0.437

High

435923

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.437

High

441872

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.437

High

455025

RS19A
Small ribosomal subunit protein eS19A

1

4

High-throughput

0.437

High

503006

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.437

High

504176

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.437

High

512404

RS6A
Small ribosomal subunit protein eS6A

1

5

High-throughput

0.437

High

512970

RS8A
Small ribosomal subunit protein eS8A

1

5

High-throughput

0.437

High

514606

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.437

High

674583

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.437

High

689415

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.437

High

747324

RSSA1
Small ribosomal subunit protein uS2A

1

4

High-throughput

0.437

High

778290

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.437

High

796695

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.437

High

796700

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

796708

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.437

High

796710

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.437

High

796713

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.437

High

796722

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.437

High

796724

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

796714

YM46
Uncharacterized protein YMR181C

2

0

High-throughput

0.307

High

713221

SEC65
Signal recognition particle subunit SEC65

1

0

High-throughput

0.269

Low

796720

ECM19
Protein ECM19

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025