HitPredict

Interactor 1: PSB5 (P30655)
Probable proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain subunit pts1) (Multicatalytic endopeptidase complex subunit pts1) (Proteasome component pts1)
Gene: pts1

Interactor 2: PSA5 (Q9UT97)
Probable proteasome subunit alpha type-5
Gene: pup2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24938783
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 272 Sp			1 247
+	Hs
		656149 PSA5_HUMAN (20-260): 1.08e-87: 262: 15.94		PSA5_HUMAN (1-242): 4.18e-104: 303: 60.74
+	Dm
		771303 PSA5_DROME (20-261): 4.21e-86: 258: 18.11		PSA2_DROME (3-243): 3.84e-99: 290: 32.37
+	Sc
		675397 PSB5_YEAST (7-270): 8.81e-84: 254: 61.89		PSA5_YEAST (1-245): 6.63e-98: 288: 66.67
+	Hs
		156230 PSA5_HUMAN (20-260): 1.08e-87: 262: 15.94		PSA7_HUMAN (8-240): 3.63e-91: 270: 40.68
+	Hs
		637325 PSA5_HUMAN (20-260): 1.08e-87: 262: 15.94		PSA1_HUMAN (3-245): 1.86e-90: 269: 34.82
+	Ss
		94704 F2Z5K2_PIG (20-260): 1.08e-87: 262: 15.94		F2Z5L7_PIG (3-245): 1.86e-90: 269: 34.82
+	Hv
		1358195 PSA1_HALVD (18-259): 1.21e-84: 255: 19.36		PSA1_HALVD (5-241): 1.75e-92: 273: 40.76
+	Hs
		656189 PSA5_HUMAN (20-260): 1.08e-87: 262: 15.94		PSA6_HUMAN (3-245): 1.6e-89: 266: 31.08
+	Hs
		637631 PSA5_HUMAN (20-260): 1.08e-87: 262: 15.94		PSA2_HUMAN (3-243): 2.58e-89: 265: 32.37
+	Hs
		656276 PSA5_HUMAN (20-260): 1.08e-87: 262: 15.94		PSMA8_HUMAN (6-240): 8.19e-89: 265: 36.89
+	Hs
		156228 PSB8_HUMAN (10-265): 6.93e-85: 256: 49.61		PSA7_HUMAN (8-240): 3.63e-91: 270: 40.68
+	Hs
		637323 PSB8_HUMAN (10-265): 6.93e-85: 256: 49.61		PSA1_HUMAN (3-245): 1.86e-90: 269: 34.82
+	Hs
		156224 PSA2_HUMAN (24-261): 8.33e-84: 252: 13.22		PSA7_HUMAN (8-240): 3.63e-91: 270: 40.68
+	Hs
		656051 PSB8_HUMAN (10-265): 6.93e-85: 256: 49.61		PSA6_HUMAN (3-245): 1.6e-89: 266: 31.08
+	Hs
		637316 PSA2_HUMAN (24-261): 8.33e-84: 252: 13.22		PSA1_HUMAN (3-245): 1.86e-90: 269: 34.82
+	Hs
		637629 PSB8_HUMAN (10-265): 6.93e-85: 256: 49.61		PSA2_HUMAN (3-243): 2.58e-89: 265: 32.37
+	Hs
		637663 PSA2_HUMAN (24-261): 8.33e-84: 252: 13.22		PSA6_HUMAN (3-245): 1.6e-89: 266: 31.08
+	Hs
		637624 PSA2_HUMAN (24-261): 8.33e-84: 252: 13.22		PSA2_HUMAN (3-243): 2.58e-89: 265: 32.37
+	Sc
		675422 PSB5_YEAST (7-270): 8.81e-84: 254: 61.89		PSA4_YEAST (6-241): 1.04e-44: 152: 37.60