Protein: UBP8
Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (mUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)

Gene: UBP8, Usp8
Organism: Mus musculus
Interactions: 15
UniProt ID: Q80U87

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0002080 - acrosomal membrane
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

509134

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

2

20

Small-scale

0.778

High

313052

STAM2
Signal transducing adapter molecule 2

2

9

Small-scale

0.624

High

972256

1433E
14-3-3 protein epsilon

2

3

Small-scale

0.619

High

1282006

RNF41
E3 ubiquitin-protein ligase NRDP1

1

20

Small-scale

0.618

High

313436

GRAP2
GRB2-related adaptor protein 2

1

18

Small-scale

0.561

High

694456

RGRF1
Ras-specific guanine nucleotide-releasing factor 1

1

4

Small-scale

0.561

High

1282008

PD1L1
Programmed cell death 1 ligand 1

1

5

Small-scale

0.553

High

205481

DNJB3
DnaJ homolog subfamily B member 3

1

3

Small-scale

0.536

High

204488

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

2

Small-scale

0.501

High

236603

ITB3
Integrin beta-3

1

3

High-throughput

0.501

High

478534

ITB1
Integrin beta-1

1

9

High-throughput

0.501

High

1221231

GRB2
Growth factor receptor-bound protein 2

1

9

Small-scale

0.501

High

1282007

Q8CGC3
Protein deacetylase HDAC6

1

9

Small-scale

0.501

High

1027941

TYY1
Transcriptional repressor protein YY1

1

3

Small-scale

0.479

High

1222286

FZD4
Frizzled-4

1

2

Small-scale

0.479

High


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Last updated: 11Aug2025