HitPredict

Interactor 1: XPO1 (P30822)
Exportin-1 (Chromosome region maintenance protein 1) (Karyopherin-124)
Gene: CRM1

Interactor 2: NU159 (P40477)
Nucleoporin NUP159 (Nuclear pore protein NUP159)
Gene: NUP159

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	10523319, 12543930, 11027275, 15557115, 15769879
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000055 - ribosomal large subunit export from nucleus GO:0000056 - ribosomal small subunit export from nucleus GO:0005634 - nucleus GO:0006611 - protein export from nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1084 Sc			1 1460
+	Hs
		162920 XPO1_HUMAN (3-1084): 0: 854: 46.40		KDM3B_HUMAN (402-1020): 1.25e-26: 121: 17.18
+	Hs
		162534 XPO1_HUMAN (3-1084): 0: 854: 46.40		NUP98_HUMAN (569-1203): 3.25e-23: 109: 13.08
+	Hs
		162539 XPO1_HUMAN (3-1084): 0: 854: 46.40		SC24C_HUMAN (361-624): 2.24e-14: 80.9: 15.61
+	Sc
		541850 XPO1_YEAST (1-1084): 0: 833: 100.00		NSP1_YEAST (404-1068): 4.68e-16: 86.1: 19.91
+	Hs
		162448 XPO1_HUMAN (3-1084): 0: 854: 46.40		NU214_HUMAN (401-760): 2.01e-09: 64.9: 17.80
+	Sc
		676198 XPO1_YEAST (1-1084): 0: 833: 100.00		NU145_YEAST (380-734): 1.66e-13: 77.9: 14.40
+	Sc
		676300 XPO1_YEAST (1-1084): 0: 833: 100.00		NU100_YEAST (414-1004): 1.29e-12: 74.9: 16.82
+	Sc
		676197 XPO1_YEAST (1-1084): 0: 833: 100.00		NUP42_YEAST (433-688): 7.05e-12: 71.5: 19.37
+	Dm
		1353152 XPO1_DROME (3-1084): 0: 789: 42.48		Q9VLS7_DROME (315-1353): 1.82e-24: 114: 8.70
+	Dm
		1353157 XPO1_DROME (3-1084): 0: 789: 42.48		NU214_DROME (438-702): 4.72e-12: 73.4: 19.39
+	Hs
		980020 XPO7_HUMAN (11-1030): 8.18e-147: 469: 13.59		IF4G1_HUMAN (430-973): 2.4e-15: 84.2: 12.81
+	Mm
		1157646 XPO7_MOUSE (11-1030): 1.87e-146: 468: 13.68		IF4G1_MOUSE (419-1012): 2.44e-14: 80.7: 11.42
+	Hs
		858024 TNPO1_HUMAN (21-967): 5.08e-125: 406: 12.09		NUP98_HUMAN (569-1203): 3.25e-23: 109: 13.08
+	Hs
		155553 TNPO2_HUMAN (21-956): 4.51e-116: 382: 11.98		NUP98_HUMAN (569-1203): 3.25e-23: 109: 13.08
+	Hs
		727340 TNPO3_HUMAN (8-1040): 5.86e-127: 412: 13.31		NU214_HUMAN (401-760): 2.01e-09: 64.9: 17.80
+	Hs
		727300 TNPO1_HUMAN (21-967): 5.08e-125: 406: 12.09		NU214_HUMAN (401-760): 2.01e-09: 64.9: 17.80
+	Xl
		1137359 Q5U4V0_XENLA (21-967): 1.15e-120: 394: 12.31		NU153_XENLA (398-864): 1.39e-10: 68.4: 18.43
+	Ce
		248185 O62332_CAEEL (10-967): 2.56e-97: 330: 11.48		Q9U3B9_CAEEL (407-673): 1.58e-10: 67.6: 16.05
+	Ce
		248165 O62332_CAEEL (10-967): 2.56e-97: 330: 11.48		CO4A1_CAEEL (139-581): 9.53e-10: 65.8: 5.64
+	Hs
		727318 XPO5_HUMAN (1-879): 1.9e-81: 291: 13.44		NU214_HUMAN (401-760): 2.01e-09: 64.9: 17.80