HitPredict

Interactor 1: HXC8 (P31273)
Homeobox protein Hox-C8 (Homeobox protein Hox-3A)
Gene: HOXC8

Interactor 2: K1C40 (Q6A162)
Keratin, type I cytoskeletal 40 (Cytokeratin-40) (CK-40) (Keratin-40) (K40) (Type I hair keratin Ka36)
Gene: KRT40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 242 Hs			1 431
+	Hs
		280534 HXC8_HUMAN (1-242): 4.21e-59: 188: 100.00		KRT34_HUMAN (29-430): 8.36e-153: 440: 62.53
+	Hs
		280511 HXB5_HUMAN (1-216): 2.62e-33: 123: 25.67		KRT34_HUMAN (29-430): 8.36e-153: 440: 62.53
+	Hs
		280546 HXA1_HUMAN (4-222): 4.75e-31: 118: 23.66		KRT34_HUMAN (29-430): 8.36e-153: 440: 62.53
+	Hs
		678960 HXC8_HUMAN (1-242): 4.21e-59: 188: 100.00		KRT35_HUMAN (2-427): 4.45e-87: 274: 59.35
+	Hs
		280776 HXC8_HUMAN (1-242): 4.21e-59: 188: 100.00		KRT36_HUMAN (7-407): 2.14e-84: 267: 63.34
+	Hs
		829849 HXA1_HUMAN (4-222): 4.75e-31: 118: 23.66		KT33B_HUMAN (23-429): 5.43e-111: 333: 58.48
+	Hs
		678914 HXC8_HUMAN (1-242): 4.21e-59: 188: 100.00		K1H1_HUMAN (48-425): 7.13e-75: 241: 63.23
+	Hs
		568010 HXB6_HUMAN (1-226): 5.11e-33: 121: 34.04		K1C15_HUMAN (88-401): 4.65e-95: 295: 52.38
+	Hs
		837921 MEOX2_HUMAN (28-223): 3.49e-32: 121: 26.24		KRT83_HUMAN (3-426): 3.19e-91: 286: 27.36
+	Hs
		837973 MEOX2_HUMAN (28-223): 3.49e-32: 121: 26.24		KRT81_HUMAN (4-426): 1.43e-90: 285: 27.65
+	Hs
		829822 HXA1_HUMAN (4-222): 4.75e-31: 118: 23.66		KRT83_HUMAN (3-426): 3.19e-91: 286: 27.36
+	Hs
		213933 MEOX2_HUMAN (28-223): 3.49e-32: 121: 26.24		KRT86_HUMAN (4-428): 1.35e-89: 282: 27.75
+	Hs
		829850 HXA1_HUMAN (4-222): 4.75e-31: 118: 23.66		KRT81_HUMAN (4-426): 1.43e-90: 285: 27.65
+	Hs
		829960 HXA1_HUMAN (4-222): 4.75e-31: 118: 23.66		KRT35_HUMAN (2-427): 4.45e-87: 274: 59.35
+	Hs
		829898 HXA1_HUMAN (4-222): 4.75e-31: 118: 23.66		K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00
+	Hs
		830038 HXA1_HUMAN (4-222): 4.75e-31: 118: 23.66		KRT82_HUMAN (21-429): 4.8e-81: 260: 26.15
+	Hs
		280960 HXA1_HUMAN (4-222): 4.75e-31: 118: 23.66		KRT38_HUMAN (1-430): 8.86e-77: 247: 49.77
+	Hs
		447251 HXB5_HUMAN (1-216): 2.62e-33: 123: 25.67		K1H1_HUMAN (48-425): 7.13e-75: 241: 63.23
+	Hs
		280862 HXA1_HUMAN (4-222): 4.75e-31: 118: 23.66		KRT37_HUMAN (1-429): 1.93e-75: 243: 48.25
+	Hs
		829857 HXA1_HUMAN (4-222): 4.75e-31: 118: 23.66		K1H1_HUMAN (48-425): 7.13e-75: 241: 63.23