Protein: CNOT6
CCR4-NOT transcription complex subunit 6 (EC 3.1.13.4) (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase)

Gene: CNOT6
Organism: Homo sapiens
Interactions: 57
UniProt ID: Q9ULM6

Gene Ontology (top 5):
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0003713 - transcription coactivator activity
GO:0003723 - RNA binding
GO:0004532 - RNA exonuclease activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1397051

CNO6L
CCR4-NOT transcription complex subunit 6-like

3

20

High-throughput

0.847

High

1460492

CNOT7
CCR4-NOT transcription complex subunit 7

8

13

Small-scale

0.746

High

64151

CNOT1
CCR4-NOT transcription complex subunit 1

5

9

Small-scale

0.712

High

1123178

FHL2
Four and a half LIM domains protein 2

1

6

High-throughput

0.691

High

866864

CAZA2
F-actin-capping protein subunit alpha-2

4

6

High-throughput

0.683

High

1453511

CNOT2
CCR4-NOT transcription complex subunit 2

4

10

Small-scale

0.683

High

1461329

CNO11
CCR4-NOT transcription complex subunit 11

4

2

High-throughput

0.683

High

867508

CAPZB
F-actin-capping protein subunit beta

3

3

High-throughput

0.662

High

1436898

CNO10
CCR4-NOT transcription complex subunit 10

3

1

Small-scale

0.662

High

273950

CNOT3
CCR4-NOT transcription complex subunit 3

3

12

Small-scale

0.657

High

1439112

TNR6C
Trinucleotide repeat-containing gene 6C protein

3

9

Small-scale

0.650

High

275469

GA45B
Growth arrest and DNA damage-inducible protein GADD45 beta

2

2

High-throughput

0.611

High

897478

TOB1
Protein Tob1

2

5

High-throughput

0.611

High

949511

NANO2
Nanos homolog 2

2

6

High-throughput

0.611

High

1315628

IZUM1
Izumo sperm-egg fusion protein 1

2

1

High-throughput

0.611

High

1336885

TNR6A
Trinucleotide repeat-containing gene 6A protein

2

9

Small-scale

0.601

High

1365390

CNOT9
CCR4-NOT transcription complex subunit 9

2

5

Small-scale

0.601

High

1420832

TB182
182 kDa tankyrase-1-binding protein

2

3

Small-scale

0.601

High

1461652

TNR6B
Trinucleotide repeat-containing gene 6B protein

2

7

Small-scale

0.601

High

480396

MMP7
Matrilysin

3

2

High-throughput

0.599

High

550516

PABP1
Polyadenylate-binding protein 1

2

7

Small-scale

0.595

High

1325731

RIBC1
RIB43A-like with coiled-coils protein 1

3

2

High-throughput

0.593

High

688339

TTP
mRNA decay activator protein ZFP36

2

5

Small-scale

0.584

High

1459119

CNOT8
CCR4-NOT transcription complex subunit 8

2

13

Small-scale

0.576

High

397202

ESR1
Estrogen receptor

2

10

High-throughput

0.571

High

340596

CNOT4
CCR4-NOT transcription complex subunit 4

1

3

Small-scale

0.561

High

1417399

TX13A
Testis-expressed protein 13A

2

2

High-throughput

0.558

High

1399949

FACOS
FANCD2 opposite strand protein

2

1

High-throughput

0.549

High

64818

EPAB2
Embryonic polyadenylate-binding protein 2

1

6

High-throughput

0.536

High

302097

SEGN
Secretagogin

1

17

High-throughput

0.536

High

462039

HS90A
Heat shock protein HSP 90-alpha

1

9

Small-scale

0.536

High

848746

MAGA9
Melanoma-associated antigen 9

1

1

High-throughput

0.536

High

915218

CAZA1
F-actin-capping protein subunit alpha-1

1

6

High-throughput

0.536

High

1364174

TM131
Transmembrane protein 131

1

4

High-throughput

0.536

High

1461653

SGT1
Protein SGT1 homolog

1

15

High-throughput

0.536

High

1461276

AGO2
Protein argonaute-2

1

6

Small-scale

0.515

High

1232146

VASN
Vasorin

1

20

High-throughput

0.514

High

927170

ATX3
Ataxin-3

1

0

High-throughput

0.513

High

1367914

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.513

High

1287153

PATL1
Protein PAT1 homolog 1

1

2

Small-scale

0.500

High

1361411

NANO1
Nanos homolog 1

1

6

High-throughput

0.489

High

50426

MEX3A
RNA-binding protein MEX3A

1

4

Small-scale

0.479

High

176574

GRRE1
Granule associated Rac and RHOG effector protein 1

1

1

High-throughput

0.479

High

590017

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

626400

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

6

High-throughput

0.479

High

1059241

TISB
mRNA decay activator protein ZFP36L1

1

5

Small-scale

0.479

High

1094752

CAF1A
Chromatin assembly factor 1 subunit A

1

5

Small-scale

0.479

High

1310675

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

7

High-throughput

0.479

High

1336327

LS14A
Protein LSM14 homolog A

1

1

High-throughput

0.479

High

1435442

EGLN3
Prolyl hydroxylase EGLN3

1

7

High-throughput

0.479

High

1460287

XPO7
Exportin-7

1

5

High-throughput

0.479

High

1461654

YTHD2
YTH domain-containing family protein 2

1

3

High-throughput

0.479

High

441519

AGAL
Alpha-galactosidase A

1

0

High-throughput

0.458

High

1428417

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.458

High

1437441

ZMAT3
Zinc finger matrin-type protein 3

1

0

Small-scale

0.458

High

1219910

OBI1
ORC ubiquitin ligase 1

1

1

Small-scale

0.457

High

1390795

S47A1
Multidrug and toxin extrusion protein 1

1

0

High-throughput

0.426

High


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Last updated: 11Aug2025