HitPredict

Interactor 1: TLX1 (P31314)
T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3)
Gene: TLX1

Interactor 2: ARI3A (Q99856)
AT-rich interactive domain-containing protein 3A (ARID domain-containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (Dead ringer-like protein 1) (E2F-binding protein 1)
Gene: ARID3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Hs			1 593
+	Hs
		213373 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		ARI3A_HUMAN (1-593): 5.33e-127: 387: 100.00
+	Hs
		1306893 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		ARI3A_HUMAN (1-593): 5.33e-127: 387: 100.00
+	Hs
		679135 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		ARI3B_HUMAN (178-588): 1.08e-77: 258: 44.73
+	Hs
		679138 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		ARI1B_HUMAN (19-552): 1.33e-62: 226: 18.80
+	Hs
		146163 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		ARI1A_HUMAN (42-571): 1.89e-59: 217: 16.15
+	Hs
		1218101 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		ARI3B_HUMAN (178-588): 1.08e-77: 258: 44.73
+	Dm
		950077 UBX_DROME (65-265): 4.1e-33: 128: 23.83		KDM5_DROME (31-462): 1.54e-77: 270: 13.65
+	Mm
		590545 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		ARI3B_MOUSE (179-588): 1.11e-75: 253: 43.41
+	Hs
		213359 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		ARI1B_HUMAN (19-552): 1.33e-62: 226: 18.80
+	Hs
		1244304 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		ARI1B_HUMAN (19-552): 1.33e-62: 226: 18.80
+	Hs
		146119 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		ARI1A_HUMAN (42-571): 1.89e-59: 217: 16.15
+	Hs
		967923 PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00		ARI1B_HUMAN (19-552): 1.33e-62: 226: 18.80
+	Hs
		1271542 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		JARD2_HUMAN (43-358): 4.63e-58: 212: 15.17
+	Hs
		146118 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		ARI1A_HUMAN (42-571): 1.89e-59: 217: 16.15
+	Hs
		967930 PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00		JARD2_HUMAN (43-358): 4.63e-58: 212: 15.17
+	Mm
		57759 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		ARI1A_MOUSE (28-571): 1.08e-56: 209: 16.46
+	Hs
		656402 PIT1_HUMAN (8-267): 3.12e-37: 136: 13.64		ARI5A_HUMAN (244-593): 1.91e-55: 199: 14.51
+	Hs
		679114 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		ARI4B_HUMAN (243-330): 8.59e-26: 115: 34.09
+	Hs
		211881 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		ARID2_HUMAN (238-342): 4.21e-28: 122: 37.38
+	Hs
		211873 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		ARI4B_HUMAN (243-330): 8.59e-26: 115: 34.09