HitPredict

Interactor 1: PSA1 (P25786)
Proteasome subunit alpha type-1 (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain) (Proteasome subunit alpha-6) (alpha-6)
Gene: PSMA1

Interactor 2: POMP (Q9Y244)
Proteasome maturation protein (Proteassemblin) (Protein UMP1 homolog) (hUMP1) (Voltage-gated K channel beta subunit 4.1)
Gene: POMP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.968

Property	Details
Experiments	31839598, 26186194, 28514442, 29568061, 33961781, 35271311, 17948026, unassigned1655
Identification Methods	cross-linking study, affinity chromatography technology, proximity labelling technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Proteasome~UMP1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 263 Hs			1 141
+	Hs
		165437 PSA7_HUMAN (6-234): 5.38e-96: 283: 33.19		POMP_HUMAN (1-141): 3.91e-75: 221: 100.00
+	Hs
		700762 PSA5_HUMAN (1-236): 4.19e-93: 275: 28.81		POMP_HUMAN (1-141): 3.91e-75: 221: 100.00
+	Hs
		954930 PSA6_HUMAN (1-240): 7.5e-93: 275: 25.00		POMP_HUMAN (1-141): 3.91e-75: 221: 100.00
+	Hs
		681746 PSA4_HUMAN (1-233): 2.18e-91: 272: 28.75		POMP_HUMAN (1-141): 3.91e-75: 221: 100.00
+	Dm
		1477600 Q9VK14_DROME (1-263): 2.77e-100: 295: 49.81		Q9VIJ5_DROME (40-140): 1.88e-46: 148: 50.50
+	Dm
		556759 PSA1_DROME (1-260): 3.17e-99: 292: 52.42		Q9VIJ5_DROME (40-140): 1.88e-46: 148: 50.50
+	Dm
		1376930 PSA5_DROME (1-237): 3.38e-92: 273: 28.86		Q9VIJ5_DROME (40-140): 1.88e-46: 148: 50.50
+	Dm
		652782 PSA71_DROME (4-233): 2.41e-38: 136: 33.48		Q9VIJ5_DROME (40-140): 1.88e-46: 148: 50.50