HitPredict

Interactor 1: DNJA1 (P31689)
DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)
Gene: DNAJA1

Interactor 2: DNJB3 (Q8WWF6)
DnaJ homolog subfamily B member 3
Gene: DNAJB3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~DnaJ, DnaJ~DnaJ_C
Common GO terms	GO:0030544 - Hsp70 protein binding GO:0051082 - unfolded protein binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 397 Hs			1 145
+	Hs
		681536 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		DNJA4_HUMAN (4-138): 7.35e-48: 160: 41.26
+	Hs
		681337 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		DNJA1_HUMAN (4-139): 7.28e-47: 157: 41.67
+	Hs
		1262155 DNJA4_HUMAN (1-397): 1.01e-159: 456: 73.37		DNJA4_HUMAN (4-138): 7.35e-48: 160: 41.26
+	Hs
		243524 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		DNJA4_HUMAN (4-138): 7.35e-48: 160: 41.26
+	Hs
		243308 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		DNJA1_HUMAN (4-139): 7.28e-47: 157: 41.67
+	Hs
		636251 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		DNJB1_HUMAN (3-110): 6.05e-24: 96.3: 50.45
+	Hs
		636382 DNJA4_HUMAN (1-397): 1.01e-159: 456: 73.37		DNJB1_HUMAN (3-110): 6.05e-24: 96.3: 50.45
+	Sc
		632971 MAS5_YEAST (1-396): 8.35e-140: 406: 45.37		MAS5_YEAST (4-138): 3.91e-42: 145: 38.62
+	Hs
		258234 DNJB4_HUMAN (5-349): 1.73e-125: 367: 32.77		DNJB6_HUMAN (1-111): 3.95e-48: 159: 79.28
+	Hs
		243297 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		DNJB1_HUMAN (3-110): 6.05e-24: 96.3: 50.45
+	Ce
		220083 O45502_CAEEL (1-397): 1.92e-128: 377: 50.12		Q20774_CAEEL (3-127): 6.65e-43: 145: 45.60
+	Ce
		183765 O16303_CAEEL (4-395): 3.16e-123: 365: 42.99		Q20774_CAEEL (3-127): 6.65e-43: 145: 45.60
+	Hs
		279354 DNJB4_HUMAN (5-349): 1.73e-125: 367: 32.77		DNJB5_HUMAN (3-110): 5.25e-42: 143: 51.85
+	Hs
		257919 DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59		DNJB6_HUMAN (1-111): 3.95e-48: 159: 79.28
+	Hs
		636434 DNJB4_HUMAN (5-349): 1.73e-125: 367: 32.77		DNJB1_HUMAN (3-110): 6.05e-24: 96.3: 50.45
+	Hs
		279277 DNJB5_HUMAN (5-347): 8.97e-125: 365: 35.21		DNJB1_HUMAN (3-110): 6.05e-24: 96.3: 50.45
+	Pf
		331987 Q8IL88_PLAF7 (2-396): 1.64e-125: 370: 37.90		O96212_PLAF7 (3-112): 5.02e-22: 90.9: 46.90