HitPredict

Interactor 1: F1712 (A8MVW0)
Protein FAM171A2
Gene: FAM171A2

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	28514442, 33961781, 35384245
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 826 Hs			1 839
+	Hs
		1081506 F1711_HUMAN (10-826): 0: 1104: 39.01		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		1083855 F1711_HUMAN (10-826): 0: 1104: 39.01		NTRK2_HUMAN (6-839): 0: 557: 52.87
+	Hs
		68174 F1712_HUMAN (1-826): 0: 1084: 100.00		NTRK2_HUMAN (6-839): 0: 557: 52.87
+	Hs
		384984 F1711_HUMAN (10-826): 0: 1104: 39.01		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		68124 F1712_HUMAN (1-826): 0: 1084: 100.00		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		508056 F1711_HUMAN (10-826): 0: 1104: 39.01		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		68129 F1712_HUMAN (1-826): 0: 1084: 100.00		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		608007 F1711_HUMAN (10-826): 0: 1104: 39.01		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		68137 F1712_HUMAN (1-826): 0: 1084: 100.00		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Mm
		546294 F171B_MOUSE (26-824): 0: 808: 28.54		NTRK2_MOUSE (6-839): 0: 555: 53.29
+	Hs
		994648 F1711_HUMAN (10-826): 0: 1104: 39.01		DDR1_HUMAN (535-824): 9.4e-68: 244: 43.63
+	Hs
		968311 F1711_HUMAN (10-826): 0: 1104: 39.01		ROR1_HUMAN (509-821): 2.63e-67: 243: 40.50
+	Hs
		968402 F1711_HUMAN (10-826): 0: 1104: 39.01		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		435668 F1711_HUMAN (10-826): 0: 1104: 39.01		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		68164 F1712_HUMAN (1-826): 0: 1084: 100.00		ROR1_HUMAN (509-821): 2.63e-67: 243: 40.50
+	Hs
		68165 F1712_HUMAN (1-826): 0: 1084: 100.00		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		1138544 F1711_HUMAN (10-826): 0: 1104: 39.01		ALK_HUMAN (513-816): 2.78e-59: 222: 39.03
+	Hs
		601533 F171B_HUMAN (28-824): 0: 806: 28.07		FGFR2_HUMAN (203-838): 1.97e-168: 510: 24.89
+	Mm
		56856 F1712_MOUSE (1-826): 0: 1077: 92.62		PTK7_MOUSE (212-394): 3.12e-10: 66.3: 17.35
+	Mm
		1062026 F171B_MOUSE (26-824): 0: 808: 28.54		PTK7_MOUSE (212-394): 3.12e-10: 66.3: 17.35