Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Interactor 2: ACAP1 (Q15027)
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (Centaurin-beta-1) (Cnt-b1)
Gene: ACAP1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.59 1.00 0.771

The method score is based on:

Property Details
Experiments 16256741
Identification Methods affinity chromatography technology, enzymatic study, in-gel kinase assay
Interaction Type physical association, direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains ArfGap~PH, BAR_3~PH, PH~PH, Ank_2~Pkinase, PH~Pkinase
Common GO terms GO:0016020 - membrane
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 480
Hs

1 740
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Mm
+ Mm
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024